TA400001 LGR5 / GPR49 antibody

Anti-LGR5 mouse mAb, clone 2A2, PE , clone OTI2A2 (formerly 2A2)

See related secondary antibodies

Search for all "LGR5 / GPR49"

0.1 ml / €365.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human, Mouse LGR5 / GPR49 OTI2A2

Product Description for LGR5 / GPR49

Mouse anti Human, Mouse LGR5 / GPR49 OTI2A2.
Presentation: Purified
Product is tested for Flow Cytometry.

Properties for LGR5 / GPR49

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, GPR67, HG38, Leucine-rich repeat-containing G-protein coupled receptor 5
Presentation Purified
Reactivity Hu, Ms
Applications F
Clonality Monoclonal
Clone OTI2A2
Host Mouse
Isotype IgG1
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Swiss Prot Num:
Human recombinant protein fragment corresponding to amino acids 250-550 of human LGR5 (NP_003658) produced in 293T Cell.
Isotype control AM03095PU-N, SM10P (for use in human samples)
Application FC:1:50
Background LGR5 (leucine-rich repeat containing G protein-coupled receptor 5) An Orphan GPCR protein, contains large extracellular domain, Stem cell biomarker for small intestine, active in colon cancer; overexpressed in ovary and liver tumors.
Product Citations
Originator or purchased from resellers:
1. Schumacher MA, Aihara E, Feng R, Engevik A, Shroyer NF, Ottemann KM, et al. The use of murine-derived fundic organoids in studies of gastric physiology. J Physiol. 2015 Apr 15;593(8):1809-27. doi: 10.1113/jphysiol.2014.283028. Epub 2015 Feb 19. PubMed PMID: 25605613.
2. Parris A, Williams MR. A human colonic crypt culture system to study regulation of stem cell-driven tissue renewal and physiological function. Methods Mol Biol. 2015;1212:141-61. doi: 10.1007/7651_2015_197. PubMed PMID: 25762290.
3. Yang Y, Wu KE, Zhao E, Li W, Shi L, Xie G, et al. B7-H1 enhances proliferation ability of gastric cancer stem-like cells as a receptor. Oncol Lett. 2015 Apr;9(4):1833-1838. Epub 2015 Feb 10. PubMed PMID: 25789052
4. Solomon, H;Dinowitz, N;Pateras, IS;Cooks, T;Shetzer, Y;Molchadsky, A;Charni, M;Rabani, S;Koifman, G;Tarcic, O;Porat, Z;Kogan-Sakin, I;Goldfinger, N;Oren, M;Harris, CC;Gorgoulis, VG;Rotter, V;2018Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers. Oncogene 2018. PubMed PMID: 29343849.
Buffer System:
TBS containing 0.1% BSA and 0.05% Azide.

Accessory Products

Proteins and/or Positive Controls

Proteins for LGR5 / GPR49 (2 products)

Catalog No. Species Pres. Purity   Source  

LGR5 / GPR49 (C-term Fc tag)

LGR5 / GPR49 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.

LGR5 / GPR49

LGR5 / GPR49 Human
  Abnova Taiwan Corp.

Positive controls for LGR5 / GPR49 (1 products)

Catalog No. Species Pres. Purity   Source  

GPR49 Lysate

Western Blot: GPR49 (LGR5) Lysate [NBL1-12509] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for LGR5
  Novus Biologicals Inc.
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