11-Deoxycorticosterone antibody

Principal name

11-Deoxycorticosterone antibody

Alternative names for 11-Deoxycorticosterone antibody

cortexone, 11 desoxycorticosterone, deoxycortone, desoxycortone, 21-hydroxyprogesterone

Available reactivities

Hu (Human), Mam (Mammalia), Ms (Mouse), Rt (Rat), Broad

Available hosts

Sheep, Rabbit

Available applications

Radioimmunoassay (R), Enzyme Immunoassay (E)

Background of 11-Deoxycorticosterone antibody

11-Deoxycorticosterone, or simply deoxycorticosterone, also known as 21-hydroxyprogesterone, is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone.  It has no significant glucocorticoid activity. 11-Deoxycorticosterone is a precursor molecule for the production of aldosterone. The major pathway for aldosterone production is in the adrenal glomerulosa zone of the adrenal gland. It is not a major secretory hormone. It is produced from progesterone by 21-beta-hydroxylase and is converted to corticosterone by 11-beta-hydroxylase. Corticosterone is then converted to aldosterone by aldosterone synthase.

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