TMED10 / TMP21 antibody
Principal name
TMED10 / TMP21 antibody
Alternative names for TMED10 / TMP21 antibody
S31I125, Transmembrane emp24 domain-containing protein 10, 21 kDa transmembrane-trafficking protein, Transmembrane protein Tmp21
Ncbi ID
NP_006818.3, 9606, NP_006818, ADZ15823.1, AAD31941, NP_081051.1, NM_053467, NM_006827
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C)
Background of TMED10 / TMP21 antibody
TMP21 (transmembrane protein Tmp21) is a type I transmembrane protein with large lumil domain belonging to p24 endoplasmic reticulum/Golgi cargo family and play key roles in protein transport, membrane structure organization and secretory pathway. TMP21 is ubiquitously expressed with highest protein levels observed in pancreas and intestines. In addition to its well established role in vesicle formation and cargo transport in ER/Golgi, TMP21 has been implicated in recruitment of small GTPase ADP-ribosylation factor 1 to Golgi apparatus and ADP-ribosylation factor 1-dependent assembly of actin in the Golgi. TMP21 forms a component of presenilin complex at the plasma membranes and modulates gamma -secretase cleavage. The cytoplasmic tails of p24 family interacts with coatomer (major component of coat protein complex I or COP-I), to facilitate transport between ER and Golgi. TMP21 cycles through the early secretory pathway between intermediate and cis-Golgi compartments, and is essential for proper organization of the Golgi apparatus. TMP21 also plays an essential and non-redundant role in earliest stages of mammalian development.
General readings
Chen F, Hasegawa H, et al. (2006). Nature. 440(7088):1208-12.Wang H, et al. (2002). J Biol Chem. 277(6):4541-50.












Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA306375 | TMED10 / TMP21 (C-term) antibody |
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| Rabbit Polyclonal TMP21 Antibody | |||||||
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Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | E, P, WB |
0.1 mg /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA306376 | TMED10 / TMP21 (Center) antibody |
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| Rabbit Polyclonal TMP21 Antibody | |||||||
![]() |
Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | E, P, WB |
0.1 mg /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA336524 | TMED10 / TMP21 antibody |
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| Rabbit Polyclonal Tmp21/p23 Antibody | |||||||
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Rabbit | Purified | Bov, Chk, Hu, Ms, Prim, Rt | C, P, WB |
0.1 ml /
€395.00
|
||
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA336525 | TMED10 / TMP21 antibody |
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| Rabbit Polyclonal Tmp21/p23 Antibody | |||||||
![]() |
Rabbit | Purified | Bov, Hu, Ms, Prim, Rb, Rt | C, WB |
0.1 ml /
€395.00
|
||
| OriGene Technologies, Inc. | |||||||
| AP07373PU-N | TMED10 / TMP21 antibody |
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![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | P, WB |
50 µg /
€425.00
|
||
| OriGene Technologies GmbH | |||||||
+1 additional image |
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| AP07791PU-N | TMED10 / TMP21 (C-term) antibody |
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![]() |
Rabbit | Purified | Hu, Ms, Rt | P, WB |
50 µg /
€425.00
|
||
| OriGene Technologies GmbH | |||||||
+1 additional image |
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Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR213216L2V | Lenti ORF particles, Tmed10 (GFP-tagged ORF) - Rat transmembrane emp24-like trafficking protein 10 (yeast) (Tmed10), 200 uL, >10^7 TU/mL |
|
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200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| RR213216L1V | Lenti ORF particles, Tmed10 (Myc-DDK-tagged ORF) - Rat transmembrane emp24-like trafficking protein 10 (yeast) (Tmed10), 200 uL, >10^7 TU/mL |
|
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200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||











+2 additional images
![Western Blot: TMP21 Antibody [TA336524] - Chicken embryo extract - Data supplied by Dr Yonghua Zhang of McGill University.](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/OriGene/NB110-57586-1-W.jpg)
![Western Blot: TMP21 Antibody [TA336525] - Detection of TMP21 in human liver lysate using TA336525.](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/OriGene/NB110-57587-1-W.jpg)


