TMEM123 / Porimin antibody
Principal name
TMEM123 / Porimin antibody
Alternative names for TMEM123 / Porimin antibody
Transmembrane protein 123, KCT3, KCT-3, PSEC0111, Pro-oncosis receptor inducing membrane injury, Keratinocytes-associated transmembrane protein 3
Ncbi ID
9606, NP_443164, NP_443164.2, NP_598500.1, NM_133739, NM_001014205, NM_052932
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)
Background of TMEM123 / Porimin antibody
TMEM123 is a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. TMEM123 is proposed to function as a cell surface receptor that mediates cell death.This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
General readings
Zhang,Z. (2004) Protein Sci. 13 (10), 2819-2824
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA350294 | TMEM123 / Porimin antibody |
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| Rabbit Polyclonal Anti-TMEM123 Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu | E, P |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| AP08472PU-N | TMEM123 / Porimin (173-188) antibody |
||||||
 |
Rabbit | IgG | Purified | Elephant, Hu, Mky, Rb | P, WB |
50 µg /
€425.00
|
|
| OriGene Technologies GmbH | |||||||
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR201906L1V | Lenti ORF particles, Tmem123 (Myc-DDK-tagged) - Mouse transmembrane protein 123 (Tmem123), 200 uL, >10^7 TU/mL |
|
 |
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR206597L2V | Lenti ORF particles, Tmem123 (GFP-tagged ORF) - Rat transmembrane protein 123 (Tmem123), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| RR206597L1V | Lenti ORF particles, Tmem123 (Myc-DDK-tagged ORF) - Rat transmembrane protein 123 (Tmem123), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||
