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TNFRSF6B / DCR3 antibody

Principal name

TNFRSF6B / DCR3 antibody

Alternative names for TNFRSF6B / DCR3 antibody

Decoy receptor 3, Decoy receptor for Fas ligand

SwissProt ID

O95407 (Human)

Gene ID

8771 (TNFRSF6B)

Ncbi ID

9606, NP_003814.1, NP_003814, AAH17065.1, NM_003823, AF104419, NM_032945

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Immunoprecipitation (IP)

Background of TNFRSF6B / DCR3 antibody

Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated by two distinct cell surface receptors, designated TNF-R1 and TNF-R2, which are expressed on most cell types. TNF function is primarily mediated through TNF-R1 signaling. Both receptors belong to the growing TNF receptor superfamily which includes FAS antigen and CD40. TNF-R1 contains a cytoplasmic motif, termed the “death domain,” that has been found to be necessary for the transduction of the apoptotic signal. The death domain is also found in several other receptors, including FAS, DR2 (or TRUNDD), DR3 (Death receptor 3), DR4, DR5 and DR6. TRUNDD, DR4 and DR5 are receptors for the apoptosis-inducing cytokine TRAIL. Non-death domain-containing receptors, designated decoy receptor 1 (DcR1) or TRID, DcR2 and DcR3, associate with specific ligands and may play a role in cellular resistance to apoptotic stimuli.

Immunoperoxidase of monoclonal antibody to TNFRSF6B on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml]

H00008771-M02

Detection limit for recombinant GST tagged TNFRSF6B is approximately 0.1ng/ml as a capture antibody.

H00008771-M02

Detection limit for recombinant GST tagged TNFRSF6B is approximately 3ng/ml as a capture antibody.

H00008771-M01

Immunohistochemistry (IHC) analysis of DcR3 antibody (Cat.-No.: AP20562PU-N) in paraffin-embedded human colon carcinoma tissue.

AP20562PU-N

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using TNFRSF6B Antibody. The picture on the right is treated with the synthesized peptide.

Immunofluorescence analysis of HepG2 cells, using TNFRSF6B Antibody. The picture on the right is treated with the synthesized peptide.

TNFRSF6B antibody (N-term) (AP54313PU-N) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TNFRSF6B antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

AP54313PU-N

TNFRSF6B Antibody (N-term) (AP54313PU-N) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the TNFRSF6B antibody detected the TNFRSF6B protein (arrow).

AP54313PU-N

Western blot analysis of DcR3 in human heart (H), brain (B), and kidney (K) tissue lysates with DcR3 antibody at 1:500 dilution.

TA306004

Immunohistochemistry of DcR1 in human heart tissue with DcR1 antibody at 1 ug/ml.

TA306004

Western blot analysis of extracts from HepG2 cells, using TNFRSF6B antibody.The lane on the right is treated with the synthesized peptide.

TA314807

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using TNFRSF6B antibody.The picture on the right is treated with the synthesized peptide.

TA314807

Immunofluorescence analysis of HepG2 cells, using TNFRSF6B antibody.The picture on the right is treated with the synthesized peptide.

TA314807

Western blot analysis on HepG2 cell lysate using TNFRSF6B Antibody

TA347594

Western blot analysis of HCT-116 cells (lane 1) and Hela cells (lane 2) using DcR3 antibody (clone B08-35).

TA352376

Formalin-fixed, paraffin-embedded human tissues were stained with 5 ug/mL B08-35, followed by incubation with biotinylated goat anti-mouse secondary antibody, followed by HRP-streptavidin. Staining was visualized with DAB peroxidase substrate and counterstained with hematoxylin. Immunohistochemical staining of DcR3 expression is shown for human breast cancer (TOP) and lung adenocarcinoma (BOTTOM).

TA352376

Primary Antibodies

Catalog No.	Host	Iso.	Pres.	React.	Applications
TA306004	TNFRSF6B / DCR3 antibody
	Rabbit Polyclonal DcR3 Antibody
	Rabbit	IgG	Purified	Hu, Ms, Rt	E, P, WB	0.1 mg / €415.00
						OriGene Technologies, Inc.
+1 additional image
TA314807	TNFRSF6B / DCR3 antibody
	Rabbit polyclonal anti-TNFRSF6B antibody
	Rabbit	IgG	Purified	Hu	E, ICC/IF, P, WB	0.1 ml / €335.00
						OriGene Technologies, Inc.
+2 additional images
TA347594	TNFRSF6B / DCR3 antibody
	Rabbit Polyclonal Anti-TNFRSF6B Antibody
	Rabbit	IgG	Purified	Hu	WB	0.1 mg / €335.00
						OriGene Technologies, Inc.
AP20562PU-N	TNFRSF6B / DCR3 antibody
	Rabbit		Aff - Purified	Hu	ICC/IF, P	0.1 mg / €370.00
						OriGene Technologies GmbH
AP54313PU-N	TNFRSF6B / DCR3 (N-term) antibody
	Rabbit	Ig	Aff - Purified	Hu	P, WB	0.4 ml / €415.00
						OriGene Technologies GmbH
+1 additional image

Lysates

Catalog No.
LY418407	TNFRSF6B overexpression lysate
		0.1 mg / €295.00
		OriGene Technologies, Inc.
LY429165	TNFRSF6B overexpression lysate
		0.1 mg / €315.00
		OriGene Technologies, Inc.

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