Barttin (54-320, His-tag) - AR51028PU-N

Product Description for Barttin

Barttin.
Presentation: Purified

Immunogen	Swiss Prot Num: Q8WZ55
Purity	> 90 % by SDS - PAGE
Background	BSND is an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. Mutations in this BSND have been associated with Bartter synd
Concentration	0.25mg/ml (determined by Bradford assay)
General Readings	Park,C.W., et al. (2011) Clin. Nephrol. 75 (SUPPL 1), 69-74Iqbal,H., et al. (2011) J. Biomed. Biotechnol. 2011, 304612
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSCQCYPKI TFVPADSDFQ GILSPKAMGL LENGLAAEMK SPSPQPPYVR LWEEAAYDQS LPDFSHIQMK VMSYSEDHRS LLAPEMGQPK LGTSDGGEGG PGDVQAWMEA AVVIHKGSDE SEGERRLTQS WPGPLACPQG PAPLASFQDD LDMDSSEGSS PNASPHDREE ACSPQQEPQG CRCPLDRFQD FALIDAPTLE DEPQEGQQWE IALPNNWQRY PRTKVEEKEA SDTGGEEPEK EEEDLYYGLP DGAGDLLPDK ELGFEPDTQG` Molecular weight: (290aa) confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT Purity: >90% by SDS - PAGE State: Liquid purified protein Purified