SM055P CD134 / TNFRSF4 antibody

See related secondary antibodies

Search for all "CD134 / TNFRSF4"

0.25 mg / €460.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rat anti Mouse CD134 / TNFRSF4 OX-86

Product Description for CD134 / TNFRSF4

Rat anti Mouse CD134 / TNFRSF4 OX-86.
Presentation: Purified
Product is tested for Frozen Sections, Flow Cytometry.

Properties for CD134 / TNFRSF4

Product Category Primary Antibodies
Target Category
Quantity 0.25 mg
Synonyms ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, TNFRSF4, TXGP1L, Tumor necrosis factor receptor superfamily member 4
Presentation Purified
Reactivity Ms
Applications C, F
Clonality Monoclonal
Clone OX-86
Host Rat
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P47741
Immunogen:
CHO cells transfected with murine OX40. Spleen cells from immunised AO rats were fused with cells of the mouse NS1 myeloma cell line.
GeneID:
22163
Isotype control SM25P, SM25PX
Application Flow Cytometry: 1/10 - 1/50; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl.
Immunohistochemistry on frozen sections.
Background The OX40 receptor is also known as CD134, ACT35, and tumour necrosis factor receptor superfamily member 4. This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX40 receptor binds to the OX40 ligand to provide a co-stimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, imply that these interactions are important in the pathogenesis of some autoimmune diseases.
Concentration 1.0 mg/ml
General Readings
  1. Higgins LM, McDonald SA, Whittle N, Crockett N, Shields JG, MacDonald TT. Regulation of T cell activation in vitro and in vivo by targeting the OX40-OX40 ligand interaction: amelioration of ongoing inflammatory bowel disease with an OX40-IgG fusion protein, but not with an OX40 ligand-IgG fusion protein. J Immunol. 1999 Jan 1;162(1):486-93. PubMed PMID: 9886424.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography on Protein G
Buffer System:
PBS, pH7.4 containing 0.09% Sodium Azide
State:
Liquid purified IgG
Purified
Specificity
Specificity:
This antibody recognises OX40 (CD134), a cell surface antigen expressed only by activated T lymphocytes.
Species:
Mouse.
Gene ID 22163

Accessory Products

  • LinkedIn