TA350069 DNAJA1 antibody

Rabbit Polyclonal Anti-DNAJA1 Antibody

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Search for all "DNAJA1"

0.1 ml / €335.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat DNAJA1

TA350069

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  • TA350069
  • TA350069

Product Description for DNAJA1

Rabbit anti Human, Mouse, Rat DNAJA1.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for DNAJA1

Product Category Primary Antibodies
Quantity 0.1 ml
Presentation Purified
Reactivity Hu, Ms, Rt
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Immunogen:
Fusion protein of human DNAJA1.
GeneID:
3301
Application ELISA: 2000-5000
WB: 500-2000
IHC: 100-300
Background DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling.
Format
Purification:
Antigen affinity purification
Buffer System:
PH7.4 PBS, 0.05% NaN3, 40% Glyceroln.
State:
Purified

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