discontinued

AP05911PU-N Tryptophan 5-hydroxylase 1 (TPH1) pSer58 antibody

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Rabbit anti Bovine, Canine, Human, Monkey, Mouse, Rabbit, Rat, Xenopus, Zebrafish Tryptophan 5-hydroxylase 1 (TPH1)

AP05911PU-N

Product Description for Tryptophan 5-hydroxylase 1 (TPH1)

Rabbit anti Bovine, Canine, Human, Monkey, Mouse, Rabbit, Rat, Xenopus, Zebrafish Tryptophan 5-hydroxylase 1 (TPH1).
Properties: pSer58
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for Tryptophan 5-hydroxylase 1 (TPH1)

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms TPRH, TRPH, Tryptophan 5-monooxygenase 1
Presentation Purified
Reactivity Bov, Can, Hu, Mky, Ms, Rb, Rt, Xen, Ze
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P17752
Immunogen:
Synthetic phosphopeptide corresponding to an amino acid sequence within Tryptophan Hydroxylase which includes phosphorylated Ser58.
GeneID:
7166
Property pSer58
Application Western Blot: 1:1000; detects a band of approximately 55kDa.
Background TPH catalyses the 5-hydroxylation of tryptophan, in the first stage in indolamine biosynthesis (e.g. serotonin and melatonin). The activity of TPH is enhanced by phosphorylation of Ser58, by cAMP dependent protein kinase (PKA) and Ca2+/calmodulin kinase II (CAMKII).
Caution (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
General Readings
  1. Banik U, Wang GA, Wagner PD, Kaufman S. Interaction of phosphorylated tryptophan hydroxylase with 14-3-3 proteins. J Biol Chem. 1997 Oct 17;272(42):26219-25. PubMed PMID: 9334190.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography
Buffer System:
10mM HEPES, pH7.5 containing 0.09% Sodium Azide, 0.01% Bovine Serum Albumin and 50% Glycerol
State:
Liquid purified Ig
Purified
Specificity
Specificity:
This antibody is specific for tryptophan hydroxylase (TPH), when phosphorylated at serine 58.
Species:
Rabbit.
Gene ID 7166

Accessory Products

Proteins and/or Positive Controls

Proteins for Tryptophan 5-hydroxylase 1 (TPH1) (5 products)

Catalog No. Species Pres. Purity   Source  

Tryptophan 5-hydroxylase 1 (TPH1)

Tryptophan 5-hydroxylase 1 (TPH1) Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.

Tryptophan 5-hydroxylase 1 (TPH1)

Tryptophan 5-hydroxylase 1 (TPH1) Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Tryptophan 5-hydroxylase 1 (TPH1)

Tryptophan 5-hydroxylase 1 (TPH1) Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Tryptophan 5-hydroxylase 1 (TPH1)

Tryptophan 5-hydroxylase 1 (TPH1) Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Tryptophan 5-hydroxylase 1 (TPH1)

Tryptophan 5-hydroxylase 1 (TPH1) Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for Tryptophan 5-hydroxylase 1 (TPH1) (3 products)

Catalog No. Species Pres. Purity   Source  

TPH1 293T Cell Transient Overexpression Lysate(Denatured)

TPH1 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

TPH1 overexpression lysate

TPH1 overexpression lysate
0.1 mg / €495.00
  OriGene Technologies, Inc.

Tryptophan Hydroxylase 1 Lysate

Western Blot: Tryptophan Hydroxylase 1 Lysate [NBL1-17216] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for TPH1.
  Novus Biologicals Inc.
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