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AP05672PU-N GABBR2 pSer783 antibody

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Rabbit anti Bovine, Chicken, Human, Monkey, Mouse, Rat, Xenopus GABBR2

AP05672PU-N

Product Description for GABBR2

Rabbit anti Bovine, Chicken, Human, Monkey, Mouse, Rat, Xenopus GABBR2.
Properties: pSer783
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for GABBR2

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms G-protein coupled receptor 51, GABA-B receptor 2, GABA-B-R2, GABBR-2, GPR51, GPRC3B, Gamma-aminobutyric acid type B receptor subunit 2, Gb2, HG20
Presentation Purified
Reactivity Bov, Chk, Hu, Mky, Ms, Rt, Xen
Applications ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O75899
Immunogen:
Synthetic phosphopeptide corresponding to an amino acid sequence within GABA B receptor 2, which includes phosphorylated Ser783.
GeneID:
9568
Property pSer783
Application Western Blot: 1:1000.
Immunofluorescence: 1:500; detects a band of approximately 102kDa in rat synaptic membrane cell lysates.
Background GABA B receptors are heterodimeric G-protein coupled receptors which are important mediators of slow neuronal inhibition in the mammalian central nervous system. The functional expression of GABA B receptors on plasma membranes is dependent upon the co-expression of GABR1 (gamma-aminobutyric acid B (GABA B) receptor 1) and GABR2. Studies have shown that the phosphorylation of GABR2 at the Ser783 site, by AMPK (5’AMPactivated protein kinase), is vital for enhancing the survival of neurons following ischemic brain injury.
Caution (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
General Readings
  1. Bowery, N.G. et al. (2002) International Union of Pharmacology XXXIII. Mammalian gammaaminobutyric acidB receptors: structure and function. Pharmacol. Rev. 54: 247 - 264.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Buffer System:
10mM Hepes pH7.5 containing 0.09% Sodium Azide (NaN3), 0.01% Bovine Serum Albumin, 50% Glycerol
State:
Liquid purified IgG
Purified
Specificity
Specificity:
This antibody specifically recognises the 102kDa transmembrane gamma-aminobutyric acid B (GABA B) receptor 2 (GABR2), when phosphorylated at Ser783.
Species:
Rat.
Gene ID 9568

Accessory Products

Proteins and/or Positive Controls

Proteins for GABBR2 (3 products)

Catalog No. Species Pres. Purity   Source  

GABBR2
GABBR2 Human
  Abnova Taiwan Corp.

GABBR2
GABBR2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

GABBR2
GABBR2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Positive controls for GABBR2 (1 products)

Catalog No. Species Pres. Purity   Source  

GABA B Receptor 2 Lysate
Western Blot: GABA B Receptor 2 Lysate [NBL1-10910] - Western Blot experiments. Left-Control; Right -Over-expression Lysate for GABBR2
  Novus Biologicals Inc.

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Rabbit IgG (H+L chain) antibody
Rabbit IgG (H+L chain) antibody Goat TRITC Rb E, F, ICC/IF
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Rabbit IgG F(ab)2 Fragment (H+L chain) antibody
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody Donkey PE Rb F
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Rabbit IgG (H+L chain, adsorbed) antibody
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Rabbit IgG (H+L chain, adsorbed) antibody
Rabbit IgG (H+L chain, adsorbed) antibody Goat Cy3
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Rabbit IgG (H+L chain, adsorbed) antibody
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Click here to see all secondary antibodies for GABBR2
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