Product Description for Annexin A5 / ANXA5
Annexin A5 / ANXA5.
Properties for Annexin A5 / ANXA5
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 30 µg |
| Synonyms | ANX5, Anchorin CII, Annexin V, Annexin-5, CBP-I, Calphobindin I, ENX2, Endonexin II, Lipocortin V, PAP-I, PP4, Placental anticoagulant protein 4, Placental anticoagulant protein I, Thromboplastin inhibitor, VAC-alpha, Vascular anticoagulant-alpha |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | >98% by SDS PAGE/HPLC analysis |
| Application | In vitro Assay. |
| Background | Annexin V is a phospholipid binding protein which binds with high affinity and selectivity to phosphatidylserine (PS), in the presence of calcium. The translocation of PS from the cytosolic leaflet to the outer leaflet of the plasma membrane, due to a loss in plasma membrane asymmetry during apoptosis, acts as an in vivo signal for the removal of the dying cell by phagocytosis. Detection of PS using Annexin V provides a reliable diagnostic tool for the indication of early programmed cell death. Annexin V has also been identified as an inhibitor of prothrombin activation in the blood coagulation cascade, and the presence of antibodies to Annexin V are associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc). |
| Concentration | 30 µg/ml |
| Storage | Prior to reconstitution store at 2-8°C. Following reconstitution store the protein (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: 6 month from despatch. |
| Source | Human |
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