discontinued

AP05915PU-N GABRA4 (C-term) antibody

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Rabbit anti Bovine, Human, Mouse, Rat GABRA4

AP05915PU-N

Product Description for GABRA4

Rabbit anti Bovine, Human, Mouse, Rat GABRA4.
Properties: (C-term)
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for GABRA4

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms GABAA Receptor alpha-4, GABRA-4, Gamma-Aminobutyric Acid Receptor subunit Alpha-4
Presentation Purified
Reactivity Bov, Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P28471
Immunogen:
Synthetic peptide corresponding to the C-Terminal region of the alpha 4 subunit of rat GABAA receptor coupled to KLH.
GeneID:
140675
Property C-term
Application Western Blot: 1:1000; detects a band of approximately 64kDa in rat brain lysates.
Background GABA A receptors are GABA gated chloride channels, which are important mediators of neuronal inhibition in the mammalian central nervous system. Activation of the GABA A site results in increased intracellular chloride concentration and hyperpolarization of the cell.
GABA A receptors are pentameric structures assembled from a family of distinct subunits. At least fourteen distinct subunits have been identified, which show distinct patterns of temporal and spatial expression.
GABA A receptors may be modulated by several drug types including benzodiazepines and barbiturates, and by phosphorylation by protein kinase C (PKC) and protein kinase A (PKA).
Caution (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography
Buffer System:
10mM HEPES, pH7.5 containing 0.09% Sodium Azide, 0.01% Bovine Serum Albumin and 50% Glycerol
State:
Liquid purified Ig
Purified
Specificity
Specificity:
This antibody is specific for the alpha 4 subunit of rat gamma-aminobutyric acid A (GABA A) receptor.
Species:
Human, Mouse, Rat, Bovine.
Gene ID 140675

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