AR05233PU-S Interleukin-1 beta / IL-1B

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50 µg / €470.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Interleukin-1 beta / IL-1B

AR05233PU-S

Product Description for Interleukin-1 beta / IL-1B

Interleukin-1 beta / IL-1B.

Properties for Interleukin-1 beta / IL-1B

Product Category Proteins & Growth Factors
Quantity 50 µg
Synonyms Catabolin, IL-1 beta, IL1 beta, IL1B, IL1F2
Species (Protein) Chicken
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P01584
Purity >85% by Ni chelate Chromatography
Application In vitro Assay.
Functional Assays.
Background Interleukin-1 (IL-1) is a pro-inflammatory cytokine secreted by many different cell types which acts upon a wide range of target cells, resulting in a diverse range of effects. The biological properties of IL-1 include the induction of B cell proliferation, stimulation of T cell proliferation in conjunction with IL-2 and the production of collagenase and prostaglandin by fibroblasts. IL-1 is also responsible for triggering the acute-phase response in the liver, and is involved in both cytokine network and vascular endothelium activation.
Concentration 250 µg/ml
General Readings
  1. Weining KC, Sick C, Kaspers B, Staeheli P. A chicken homolog of mammalian interleukin-1 beta: cDNA cloning and purification of active recombinant protein. Eur J Biochem. 1998 Dec 15;258(3):994-1000. PubMed PMID: 9990317.
  2. Gyorfy, Z. et al. (2003) Truncated chicken interleukin-1 beta with increased biologic activity. J. Interferon and Cytokine Research 23: 223-228.
Storage Store the protein at -20°C.
Avoid repeated freezing and thawing.
Shelf life: 3 month from despatch.
Source Chicken
Description
Description:
His-tagged recombinant chicken interleukin-1 beta expressed in E.coli. This antigen induces corticosterone secretion in vivo(1) and is the immunogen used to produce chicken IL-1beta antibody product code SP2127A.
Molecular weight:
23kD
Format
Buffer System:
Phosphate buffered saline
Purity:
>85% by Ni chelate Chromatography
State:
Liquid purified protein
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