AGR2 (21-175, His-tag) - AR09003PU-S

Product Description for AGR2

AGR2.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	AG-2, AG2, Anterior gradient protein 2 homolog, HPC8, Secreted cement gland protein XAG-2 homolog
Presentation	Purified
Molecular weight	21.9 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: O95994
Purity	> 95 % by SDS PAGE
Background	AGR2 (Anterior gradient 2 homolog) is the human orthologue of the secreted Xenopus laevis Anterior Gradient protein (XAG-2). This is a small, possibly secreted molecule of yet weakly defined functions that is widely expressed in human tissues. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor.
Concentration	1.0 mg/ml (determined by Bradford assay)
General Readings	F.R. Fritzsche. et al., (2007). Histol Histopathol. 22 : 703-708. Fletcher GC, Patel S, Tyson K. et al., (2003) Br J Cancer 24;88(4) : 579-85. Liu D, Rudland PS, Sibson DR, et al., (2005) Cancer Res. 65 : 3796-805.
Storage	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human AGR2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSRDTT VKPGAKKDTK DSRPKLPQTL SRGWGDQLIW TQTYEEALYK SKTSNKPLMI IHHLDECPHS QALKKVFAEN KEIQKLAEQF VLLNLVYETT DKHLSPDGQY VPRIMFVDPS LTVRADITGR YSNRLYAYEP ADTALLLDNM KKALKLLKTE L` Molecular weight: (191 aa), confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris 8.0, 1mM DTT, 10% glycerol, 1 mM EDTA Purity: >95% by SDS PAGE State: Liquid purified protein Purified