Geminin (His-tag) - AR09030PU-L | acris-antibodies.com

Product Description for Geminin

Geminin.
Presentation: Purified

Immunogen	Swiss Prot Num: O75496
Purity	> 95 % >/= 95% by SDS PAGE
Background	Geminin is a 25 kDa protein, which inhibits DNA replication and is degraded during the mitotic phase of the cell cycle. Geminin controls replication by binding to the licensing factor Cdt1, and is involved in neural differentiation. In addition, geminin directly interacts with Six3 and Hox homeodomain proteins during embryogenesis and inhibits their functions.
Concentration	1.0 mg/ml
General Readings	Pitulescu M. et al (2005) Cell Mol Life Sci. 62(13):1425-33. Luo L. et al (2004) Nature. 427(6976):749-53.
Storage	Store (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Source	E. coli
Description	Description: Recombinant His-tagged human Geminin AA Sequence: `MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMNPS MKQKQEEIKE NIKNSSVPRR TLKMIQPSAS GSLVGRENEL SAGLSKRKHR NDHLTSTTSS PGVIVPESSE NKNLGGVTQE SFDLMIKENP SSQYWKEVAE KRRKALYEAL KENEKLHKEI EQKDNEIARL KKENKELAEV AEHVQYMAEL IERLNGEPLD NFESLDNQEF DSEEETVEDS LVEDSEIGTC AEGTVSSSTD AKPCI` Molecular weight: 27.7 kDa (245 aa)
Format	Buffer System: 20 mM Tris (pH 8.0), 100 mM NaCl, 10% Glycerol Purity: >95% >/= 95% by SDS PAGE State: Liquid purified protein Purified