Product Description for GADD45G
GADD45G.
Presentation: Purified
Presentation: Purified
Properties for GADD45G
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | CR6, Cytokine-responsive protein CR6, DDIT2, DNA-damage-inducible transcript 2, Growth arrest and DNA-damage-inducible protein GADD45 gamma |
| Presentation | Purified |
| Molecular weight | 17.1 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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| Purity | > 95 % by SDS - PAGE |
| Background | GADD45G is a member of GADD45 family (GADD45α, β, and γ) that are nuclear proteins to interact with various proteins implicated in stress responses and cell-cycle-related proteins. The function of GADD45 proteins is involved in growth-regulatory mechanisms and apoptosis. GADD45G protein responds to environmental stresses by mediating activation of p38/JNK pathway via MTK1/MEKK4 kinase and its transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Zerbini LF., et al. (2004) PNAS 101(37), 13618-23. |
| Storage | Store (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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