AR09163PU-N NAT6 / FUS2 (1-308, His-tag)

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50 µg / €1,070.00
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NAT6 / FUS2

Product Description for NAT6 / FUS2

NAT6 / FUS2.
Presentation: Purified

Properties for NAT6 / FUS2

Product Category Proteins & Growth Factors
Quantity 50 µg
Synonyms FUS-, N-acetyltransferase 6, Protein fusion-2
Presentation Purified
Molecular weight 35.9 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q93015
Purity > 95 % by SDS - PAGE
Background N-acetyltransferase, also known as FUS2 (NAT6), is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to acrylamines. This enzyme is physically localized in the cytoplasm and its activity has been documented by its feasibility to acetylate the N-terminus of proteins using a ping-pong-like mechanism and by its substrate specificity. Since the Fus-2 gene maps to the chromosomal region 3p21.3, which contains at least one tumor suppressor gene, the N-acetyltransferase functions of Fus-2 may be relevant to its potential role in cancer.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings
  • Zegerman P., et al. (2000). Oncogene. 19(1):161-3.
  • Gatphayak K., et al. (2004). Gene. 337:105-11.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human N-acetyltransferase 6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MQELTLSPGP AKLTPTLDPT HRMELILSTS PAELTLDPAC QPKLPLDSTC QPEMTFNPGP TELTLDPEHQ PEETPAPSLA ELTLEPVHRR PELLDACADL INDQWPRSRT SRLHSLGQSS DAFPLCLMLL SPHPTLEAAP VVVGHARLSR VLNQPQSLLV ETVVVARALR GRGFGRRLME GLEVFARARG FRKLHLTTHD QVHFYTHLGY QLGEPVQGLV FTSRRLPATL LNAFPTAPSP RPPRKAPNLT AQAAPRGPKG PPLPPPPPLP ECLTISPPVP SGPPSKSLLE TQYQNVRGRP IFWMEKDI
Molecular weight:
(328 aa), confirmed by MALDI-TOF. Molecular weight on SDS-PAGE will appear higher.
Format
Buffer System:
20 mM Mes buffer (pH 5.0) containing 150mM NaCl, 30% glycerol
Purity:
>95% by SDS - PAGE
State:
Liquid purified protein
Purified
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