TBCA (1-108) - AR09214PU-L | acris-antibodies.com

Product Description for TBCA

TBCA.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.5 mg
Synonyms	TCP1-chaperonin cofactor A, Tubulin-folding cofactor A, Tubulin-specific chaperone A
Presentation	Purified
Molecular weight	12.8 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: O75347
Purity	> 95 % by SDS - PAGE
Background	Tubulin folding cofactor A, also known as TBCA, is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin in a quasi-native confirmation. This protein is essential for cell viability and its knockdown produces a decrease in the amount of soluble tubulin, modifications in microtubules and G1 cell cycle arrest.
Concentration	1 mg/ml (determined by Bradford assay)
General Readings	Nolasco S., et al. (2005). FEBS Lett. 579(17):3515-24.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human TBCA protein was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MADPRVRQIK IKTGVVKRLV KEKVMYEKEA KQQEEKIEKM RAEDGENYDI KKQAEILQES RMMIPDCQRR LEAAYLDLQR ILENEKDLEE AEEYKEARLV LDSVKLEA` Molecular weight: (108 aa)
Format	Buffer System: 20 mM Tris-HCl buffer pH 7.5 containing 1 mM DTT, 10% glycerol Purity: >95% by SDS - PAGE State: Liquid purified protein Purified