Product Description for PRL3 / PTP4A3
PRL3 / PTP4A3.
Presentation: Purified
Presentation: Purified
Properties for PRL3 / PTP4A3
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | PRL-3, PRL-R, Protein tyrosine phosphatase type IVA 3, Protein-tyrosine phosphatase 4a3, Protein-tyrosine phosphatase of regenerating liver 3 |
| Presentation | Purified |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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|---|---|
| Purity | > 95 % by SDS - PAGE |
| Background | Protein tyrosine phosphatase type IVA 3 (PRL-3), as known as PTP4A3, belongs to a small class of prenylated protein tyrosine phosphatases (PTPs) that remove phosphate modifications from tyrosine residues on proteins. This protein enhances cell proliferation, cell motility and invasive activity. High levels of PRL-3 expression are associated with tumorigenesis and metastasis, thus it is overexpressed in metastatic colorectal, ovarian, liver and skin cancers. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Ooki A., et al. (2009). Oncol Rep. 21(6):1467-75. Wang Z., et al. (2009). Ann Surg Oncol. 16(1):208-19. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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