BIN069 Hepatitis B Core Antigen / HBcAg (1-144) (ayw)

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0.5 mg / €840.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Hepatitis B Core Antigen / HBcAg

BIN069

Product Description for Hepatitis B Core Antigen / HBcAg

Hepatitis B Core Antigen / HBcAg.
Presentation: Purified

Properties for Hepatitis B Core Antigen / HBcAg

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Synonyms HBV Capsid protein, HBV Core protein, p21.5
Presentation Purified
Source E. coli
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH

Datasheet Extract

Purity 95 % pure by SDS-PAGE
Background Hepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection.
The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection.
Concentration 1.0 mg/ml (OD280 nm)
General Readings
  1. Kondo Y, Ueno Y, Kobayashi K, Kakazu E, Shiina M, Inoue J, et al. Hepatitis B virus replication could enhance regulatory T cell activity by producing soluble heat shock protein 60 from hepatocytes. J Infect Dis. 2010 Jul 15;202(2):202-13. doi: 10.1086/653496. PubMed PMID: 20533879.
Storage Store the antigen at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid multiple freeze/thaw cycles.
Shelf life: one year from despatch.
Description
Description:
HBV core antigen (HBcAg) recombinant. Amino acids 1-144 of HBV core antigen, 14 kDa. Deleted DNA binding domain.Cloned from HBV 320 genome.Does not contain fusion partner.
Format
Buffer System:
7.5 mM Phosphate buffer, 75 mM NaCl, pH 7.2 containing 50% Glycerol without preservatives
Purity:
95% pure by SDS-PAGE
State:
Liquid purified fraction
Purified
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