Transthyretin / Prealbumin (21-147) - AR09342PU-L

Product Description for Transthyretin / Prealbumin

Transthyretin / Prealbumin.
Presentation: Purified

Immunogen	Swiss Prot Num: P02766
Purity	> 95 % by SDS - PAGE
Background	Prealbumin, also known Transthyretin, is a tetrameric human plasma protein that is synthesized mainly in the liver. This protein transports the thyroid hormone thyroxine (T4) and retinol (Vitamin A). It is the best indicator of protein-energy malnutrition because it has a circulating half life of 2 days and responds rapidly to changes in nutritional status. Also point-mutations of its gene are known to be associated with the amyloid diseases senile systemic amyloidosis (SSA), familial amyloid polyneuropathy (FAP), and familial amyloid cardiomyopathy (FAC).
Concentration	1.0 mg/ml (determined by Bradford assay)
General Readings	Ando Y., et al. (2009) Rinsho Byori. 57(3):228-35. Shenkin A., et al. (2006) Clin Chem. 52(12):2177-9.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human Prealbumin was expressed in E.coli and purified by using conventional chromatography. N-terminal Sequence Analysis: Met-Lys-Ile Ile-Glu-Glu AA Sequence: `MGPTGTGESK CPLMVKVLDA VRGSPAINVA VHVFRKAADD TWEPFASGKT SESGELHGLT TEEEFVEGIY KVEIDTKSYW KALGISPFHE HAEVVFTAND SGPRRYTIAA LLSPYSYSTT AVVTNPKE` Molecular weight: (128 amino acids)
Format	Buffer System: PBS, pH 7.4, containing 10% Glycerol Purity: >95% by SDS - PAGE State: Liquid purified protein Purified