discontinued

SM2210B CD29 / Integrin beta-1 antibody

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Hamster anti Mouse, Rat CD29 / Integrin beta-1 HM beta 1.1

SM2210B

Product Description for CD29 / Integrin beta-1

Hamster anti Mouse, Rat CD29 / Integrin beta-1 HM beta 1.1.
Presentation: Biotin
Product is tested for Flow Cytometry.

Properties for CD29 / Integrin beta-1

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms FNRB, Fibronectin receptor subunit beta, ITGB1, Integrin VLA-4 subunit beta, MDF2, MSK12
Presentation Biotin
Reactivity Ms, Rt
Applications F
Clonality Monoclonal
Clone HM beta 1.1
Host Hamster
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P09055
Immunogen:
Purified mouse VLA-4 antigen.
Spleen cells from immunised Armenian hamsters were fused with cells of the P3U1 mouse myeloma cell line.
GeneID:
16412
Application Flow Cytometry: Use 10 µl of the suggested working dilution to label 10e6 cells in 100 µl.
The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
Background CD29 is a 110KD cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. CD29 forms non-covalent bonds with the integrin alpha subunits, including CD51 and CD49a-f, to form heterodimers. The ligands for these heterodimers include collagen, fibronectin, laminin and vascular adhesion molecule-1. In the immune system beta 1 integrins play an important role in cell adhesion, migration, activation and differentiation.
Concentration 0.1 mg/ml
General Readings
  1. Noto K, Kato K, Okumura K, Yagita H. Identification and functional characterization of mouse CD29 with a mAb. Int Immunol. 1995 May;7(5):835-42. PubMed PMID: 7547709.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Label:
Biotin
Purification:
Affinity Chromatography on Protein G.
Buffer System:
PBS, pH7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
State:
Liquid purified IgG fraction.
Specificity
Specificity:
This antibody recognises the integrin beta 1 subunit (CD29).
Clone HM beta 1.1 is reported to inhibit beta 1 integrin mediated adhesion. We recommend the use of SM2210LE for this purpose.
Species:
Mouse and Rat.
Gene ID 16412

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