discontinued

BIN020 HIV-1 gp41

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HIV-1

BIN020

Product Description for HIV-1

HIV-1.
Presentation: Azide Free

Properties for HIV-1

Product Category Proteins & Growth Factors
Quantity 1 mg
Synonyms HIV-I, HIV1, Human immunodeficiency virus type 1
Presentation Azide Free
Source Pichia pastoris
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH

Datasheet Extract

Purity Purity compares with refernce lot (verified by SDS-PAGE).
Add. information Internal thread vial. Centrifuge product before opening!
Application Suitable for ELISA and Western blot.
Background HIV is a highly variable virus which mutates very readily. This means there are many different strains of HIV, even within the body of a single infected person. The strains of HIV1 can be classified into three groups : the "major" group M, the "outlier" group O and the "new" group N. These three groups may represent three separate introductions of simian immunodeficiency virus into humans. Group O appears to be restricted to West-Central Africa and group N, discovered in 1998 in Cameroon, is extremely rare. More than 90% of HIV1 infections belong to HIV1 group M.
Concentration 1.7 mg/ml (BCA)
Product Citations
Purchased from Acris:
  1. Gordts SC, Renders M, Férir G, Huskens D, Van Damme EJ, Peumans W, et al. NICTABA and UDA, two GlcNAc-binding lectins with unique antiviral activity profiles. J Antimicrob Chemother. 2015 Jun;70(6):1674-85. doi: 10.1093/jac/dkv034. Epub 2015 Feb 19. PubMed PMID: 25700718.
  2. Rivero-Buceta E, Doyagüez EG, Colomer I, Quesada E, Mathys L, Noppen S, et al. Tryptophan dendrimers that inhibit HIV replication, prevent virus entry and bind to the HIV envelope glycoproteins gp120 and gp41. Eur J Med Chem. 2015 Oct 21;106:34-43. doi: 10.1016/j.ejmech.2015.10.031. PubMed PMID: 26513643.
Storage Upon receipt, store (in aliquots) at -20°C to -80°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant ecto-domain of HIV-1 gp41 (amino acids 541-682 from strain HxB2). Contains a 6 histidine fusion partner. Reacts with HIV-1 positive human sera and monoclonal antibodies specific for conformational and linear epitopes as determined by Western blot. Three major immunospecific bands migrating between 20 and 30 kDa, minor bands between 20 and 30 kDa and at ~14 and ~7 kDa, and an aggregation smear at ~35 kDa and greater.
Format
Buffer System:
1M Urea, 0.02M Sodium Phosphate, 0.5M Sodium Chloride, pH 7.4 ± 0.2 containing no preservatives
Purity:
Purity compares with refernce lot (verified by SDS-PAGE).
State:
Liquid purified protein
Azide Free
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