Caspase-12 Control Peptide - AP00089CP-N

Product Description for Caspase-12

anti Caspase-12.
Properties: Control Peptide
Presentation: Purified

Product Category	Control Peptides
Quantity	50 µg
Synonyms	CASP-12, CASP12, Inactive caspase-12
Presentation	Purified
Clonality	Polyclonal
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Polyclonal Antibodies (de)

Immunogen	Swiss Prot Num: O08736 GeneID: 12364
Application	Western blot: It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C.
Background	The Caspase family of cysteine proteases play a key role in apoptosis. Three distinct signaling pathways lead to apoptosis. The death receptor and mitochondrion pathways are the main ways in which the key apoptotic proteases Caspase 8 and Caspase 9, respectively, are involved. Caspase 12 is localised to the ER and is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. Caspase 12 is believed to mediate apoptosis in response to endoplasmic reticulum stress. Caspase 12 is colocalized to the ER with several proteins that are involved in Alzheimers disease including g-secretase presenilin and b-amyloid precursor protein (APP).
Concentration	0.2 mg/ml
Storage	Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Format	Buffer System: PBS, pH 7.2, containing 0.1% BSA and 0.02% thimerosal Purity: purified State: Liquid peptide Purified
Specificity	Specificity: Control peptide fro antibody AP00089PU-N only.
Gene ID	12364