Product Description for CD121a / IL1R1
Mouse anti Human CD121a / IL1R1 BDI204.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Radioimmunoassay.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Radioimmunoassay.
Properties for CD121a / IL1R1
| Product Category | Primary Antibodies |
|---|---|
| Quantity | 0.2 mg |
| Synonyms | IL-1R-alpha, IL1R, IL1RA, IL1RT1, Interleukin-1 receptor alpha, Interleukin-1 receptor type 1, Interleukin-1 receptor type I |
| Presentation | Purified |
| Reactivity | Hu |
| Applications | E, ICC/IF, R |
| Clonality | Monoclonal |
| Clone | BDI204 |
| Host | Mouse |
| Isotype | IgG2a |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Monoclonal Antibodies (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Isotype control | AM03096PU-N |
| Application | ELISA: Can be used as capture reagents or second antibody at a concentration of 5µg/ml. RIA: Concentrations of 20-30ng/ml of these antibodies will bind radiolabeled IL-1 receptor in a radioimmunoassay format. Immunohistochemistry: IL-1 receptor can be detected on cultured cells using antibody concentrations of 10-100µg/ml. |
| Background | IL1 binds antigen CD121a, which is a transmembrane glycoprotein and a member of the immunoglobulin superfamily expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. CD121a binds the mature forms of IL1 alpha, IL1 beta, and IL1 Ra proteins. High affinity binding and signalling by the type I IL1 receptor requires CD121a and the accessory protein, IL1 R AcP, which does not bind IL1 alone, but forms a dimer capable of binding IL1. Interleukin 1 (IL1), which has a role as a mediator in inflammation, consists of 2 separate but related proteins, IL1 alpha and IL1 beta. Cell surface receptors for the 2 forms of IL1 are identical. IL1R Type I contains a single membrane spanning segment, a large cytoplasmic region, and an extracellular, IL1 binding portion composed of 3 immunoglobulin like domains. |
| Concentration | 2.2mg/ml (OD280nm) |
| Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Format |
|
| Specificity |
|
| Gene ID | 3554 |
Accessory Products
Proteins and/or Positive Controls
Proteins for CD121a / IL1R1 (11 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| TP723862 |
CD121a / IL1R1 |
||||||
|
Human |
> 95 % Preparation: . Purity Detail: >95%, as determined by Coomassie stained SDS-PAGE. |
HEK293 cells |
10 µg /
€120.00
|
|||
| OriGene Technologies, Inc. | |||||||
| AR51968PU-N |
CD121a / IL1R1 (21-336, His-tag) |
||||||
|
Human | Purified | > 95 % by SDS - PAGE | Insect cells |
0.25 mg /
€1,070.00
|
||
| OriGene Technologies GmbH | |||||||
| AR51968PU-S |
CD121a / IL1R1 (21-336, His-tag) |
||||||
|
|
Human | Purified | > 95 % by SDS - PAGE | Insect cells |
50 µg /
€320.00
|
||
| OriGene Technologies GmbH | |||||||
| H00003554-G01 |
CD121a / IL1R1 |
||||||
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| H00003554-Q01-10 |
CD121a / IL1R1 |
||||||
|
|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue. | in vitro transl. | ||||
| Abnova Taiwan Corp. | |||||||
| H00003554-Q01-25 |
CD121a / IL1R1 |
||||||
|
|
Human | 12.5% SDS-PAGE Stained with Coomassie Blue. | in vitro transl. | ||||
| Abnova Taiwan Corp. | |||||||
| P1337 |
CD121a / IL1R1 |
||||||
|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| P3674 |
CD121a / IL1R1 |
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|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| P3829 |
CD121a / IL1R1 |
||||||
|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| NBC1-18464 |
CD121a / IL1R1 |
||||||
![SDS-Page:IL1RN/IL1RA Protein [NBC1-18464] - Interleukin-1 receptor antagonist, 17.2kDa (153aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/IL1%20Receptor%20I%20Protein-SDS-Page-NBC1-18464-img0001.jpg)
|
Protein | ||||||
| Novus Biologicals Inc. | |||||||
| NBP1-46070 |
CD121a / IL1R1 |
||||||
![Western Blot: IL1 Receptor I Protein [NBP1-46070] - Lane 1 – MW markers; Lane 2 – IL-1RI-Fc Chimera; Lane 3 – IL-1RI-Fc Chimera treated with PNGase F to remove potential N-linked glycans; Lane 4 – IL-1RI-Fc Chimera treated with a glycosidase cocktail to remove potential N- and O-linked glycans. 10 µg protein loaded per lane; Deep Purple™ stained. Drop in MW after treatment with PNGase F indicates presence of N-linked glycans. Additional bands in lane 3 and lane 4 are glycosidase enzymes.](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/IL1%20Receptor%20I%20Protein-Western%20Blot-NBP1-46070-img0001.jpg)
|
Human | Purified | |||||
| Novus Biologicals Inc. | |||||||
Positive controls for CD121a / IL1R1 (2 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00003554-T01 |
IL1R1 293T Cell Transient Overexpression Lysate(Denatured) |
||||||
|
|||||||
| Abnova Taiwan Corp. | |||||||
| LY424475 |
IL1R1 overexpression lysate |
||||||
|
0.1 mg /
€295.00
|
||||||
| OriGene Technologies, Inc. | |||||||
Recommended Secondary Antibodies for CD121a / IL1R1 (11 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1253AP |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | AP | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253B |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Biotin | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253F |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | FITC | E, ICC/IF | ||||
| OriGene Technologies GmbH | |||||||
| R1253HRP |
Mouse IgG (H+L chain) antibody |
||||||
|
Rabbit | HRP | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253TR |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Texas Red | ICC/IF | ||||
| OriGene Technologies GmbH | |||||||
| R1403R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Rabbit | PE | F | ||||
| OriGene Technologies GmbH | |||||||
| R1405R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Goat | PE | |||||
| OriGene Technologies GmbH | |||||||
| R1455R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
||||||
|
|
Donkey | PE | |||||
| OriGene Technologies GmbH | |||||||
| R1457C2 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy2 | |||||
| OriGene Technologies GmbH | |||||||
| R1457C3 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy3 | |||||
| OriGene Technologies GmbH | |||||||
| R1457C5 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy5 | |||||
| OriGene Technologies GmbH | |||||||
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