AR09452PU-N Calreticulin (18-417, His-tag)

Search for all "Calreticulin"

0.1 mg / €400.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Calreticulin

AR09452PU-N

More Views

  • AR09452PU-N

Product Description for Calreticulin

Calreticulin.
Presentation: Purified

Properties for Calreticulin

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms CALR, CRP55, CRTC, Calregulin, ERp60, HACBP, grp60
Presentation Purified
Molecular weight 48.7 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P27797
Purity > 85 % by SDS - PAGE
Background Calreticulin is the major calcium binding protein found in smooth muscle sarcoplasmic reticulum (SR) and non-muscle endoplasmic reticulum (ER) membranes. Calreticulin can inhibit the binding of androgen receptor to its hormone-responsive DNA element and can inhibit androgen receptor and retinoic acid receptor transcriptional activities in vivo, as well as retinoic acid-induced neuronal differentiation. Thus, Calreticulin can act as an important modulator of the regulation of gene transcription by nuclear hormone receptors.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Kropp LE., et al. (2010) J Immunol. 184(10):5619-27.
Singh P., et al. (2010) J Biochem. 147(5):625-32.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human Calreticulin protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MEPAVYFKEQ FLDGDGWTSR WIESKHKSDF GKFVLSSGKF YGDEEKDKGL QTSQDARFYA LSASFEPFSN KGQTLVVQFT VKHEQNIDCG GGYVKLFPNS LDQTDMHGDS EYNIMFGPDI CGPGTKKVHV IFNYKGKNVL INKDIRCKDD EFTHLYTLIV RPDNTYEVKI DNSQVESGSL EDDWDFLPPK KIKDPDASKP EDWDERAKID DPTDSKPEDW DKPEHIPDPD AKKPEDWDEE MDGEWEPPVI QNPEYKGEWK PRQIDNPDYK GTWIHPEIDN PEYSPDPSIY AYDNFGVLGL DLWQVKSGTI FDNFLITNDE AYAEEFGNET WGVTKAAEKQ MKDKQDEEQR LKEEEEDKKR KEEEEAEDKE DDEDKDEDEE DEEDKEEDEE EDVPGQAKDE L
Molecular weight:
(421 aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 0.1 M Nacl, 10% glycerol
Purity:
>85% by SDS - PAGE
State:
Liquid purified protein
Purified
  • LinkedIn