Product Description for Calreticulin
Calreticulin.
Presentation: Purified
Presentation: Purified
Properties for Calreticulin
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | CALR, CRP55, CRTC, Calregulin, ERp60, HACBP, grp60 |
| Presentation | Purified |
| Molecular weight | 48.7 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | Calreticulin is the major calcium binding protein found in smooth muscle sarcoplasmic reticulum (SR) and non-muscle endoplasmic reticulum (ER) membranes. Calreticulin can inhibit the binding of androgen receptor to its hormone-responsive DNA element and can inhibit androgen receptor and retinoic acid receptor transcriptional activities in vivo, as well as retinoic acid-induced neuronal differentiation. Thus, Calreticulin can act as an important modulator of the regulation of gene transcription by nuclear hormone receptors. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Kropp LE., et al. (2010) J Immunol. 184(10):5619-27. Singh P., et al. (2010) J Biochem. 147(5):625-32. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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