Product Description for Glutaredoxin-3 / GLRX3
Glutaredoxin-3 / GLRX3.
Presentation: Purified
Presentation: Purified
Properties for Glutaredoxin-3 / GLRX3
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | GRX3, HUSSY-22, PICOT, PKC-interacting cousin of thioredoxin, PKC-theta-interacting protein, TXNL2, Thioredoxin-like protein 2 |
| Presentation | Purified |
| Molecular weight | 39.6 |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 95 % by SDS - PAGE |
| Background | Glutaredoxin (GRX) is member of the thiol-disulfide oxidoreductase family. Glutraredoxin catalyzes the reversible reduction of protein-glutathionyl mixed disulfides to free sulfhydryl groups though a monothiol mechanism. Glutaredoxin-3 (Grx3/PICOT) is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals. It has been shown to interact with PRKCQ. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Witte S., et al. (2000) J Biol Chem 275(3): 1902–9. Haunhorst P., et al. (2010) Biochem Biophys Res Commun. 394(2):372-6. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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