PDE6D / PDED (1-150, His-tag) - AR09463PU-N

Product Description for PDE6D / PDED

PDE6D / PDED.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	5'-cyclic phosphodiesterase subunit delta, GMP-PDE delta, Phosphodiesterase 6D, Phosphodiesterase-6D cGMP-specific, Protein p17, Retinal rod rhodopsin-sensitive cGMP 3'
Presentation	Purified
Molecular weight	18.4 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: O43924
Purity	> 90 % by SDS-PAGE
Background	Human PDE6D was originally identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. Catalytically active PDE6 is a heterodimer (αβ) that is regulated by two inhibitory γ subunits. As PDE6D does not modify the catalytic properties of PDEαβ, its function is still unresolved.
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Zhang H., et al, (2007) Proc Natl Acad Sci U S A. 104(21):8857-62. Dekomien., G. et al. (2003) Genet Sel Evol. 35(4):445-56.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human PDE6D, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH` Molecular weight: (158 aa), confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1 mM DTT, 100 mM NaCl Purity: >90% by SDS-PAGE State: Liquid purified protein Purified