Product Description for Annexin A1 / ANXA1
Annexin A1 / ANXA1.
Presentation: Purified
Presentation: Purified
Properties for Annexin A1 / ANXA1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 20 µg |
| Synonyms | ANX1, Annexin I, Annexin-1, Calpactin II, Chromobindin-9, LPC1, Lipocortin I, Phospholipase A2 inhibitory protein, p35 |
| Presentation | Purified |
| Molecular weight | 38.7 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | Annexin A1, also known as Lipocortin I, belongs to a family of Ca(2+)-dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. It promotes membrane fusion and is also involved in exocytosis. Since Annexin A1 has phospholipase A2 inhibitory activity to bind from two to four calcium ions with high affinity, this protein may have potential anti-inflammatory activity. The detection of this protein by immunocytochemical means reportedly provides a simple, highly sensitive and specific assay for diagnosis of hairy cell leukemia. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Lim LH., et al. (2007). FASEB J. 21(4):968-75. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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