AR09191PU-N PINX1 (1-328, His-tag)

Search for all "PINX1"

0.1 mg / €400.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

PINX1

AR09191PU-N

More Views

  • AR09191PU-N

Product Description for PINX1

PINX1.
Presentation: Purified

Properties for PINX1

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms LPTL, LPTS, Liver-related putative tumor suppressor, Pin2-interacting protein X1, Protein 67-11-3, TRF1-interacting protein 1
Presentation Purified
Molecular weight 39.1 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q96BK5
Purity > 95 % by SDS - PAGE
Background PINX1 (PIN2-interacting protein 1) is a ubiquitously expressed protein that localizes to nucleoli and telomere speckles. This protein contains a TID (telomerase inhibiting domain) domain which is capable of binding MCRS1, TERT and TERF1. PINX1 has been shown to be a potent telomerase inhibitor and putative tumor suppressor.
Concentration 1 mg/ml (determined by Bradford assay)
General Readings Zhou XZ., et al. (2001). Cell. 107(3):347-59.
Yoo JE., et al. (2009). J Mol Biol. 388(5):928-40.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human PINX1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MSMLAERRRK QKWAVDPQNT AWSNDDSKFG QRMLEKMGWS KGKGLGAQEH GATDHIKVQV KNNHLGLGAT INNEDNWIAH QDDFNQLLAE LNTCHGQETT DSSDKKEKKS FSLEEKSKIS KNRVHYMKFT KGKDLSSRSK TDLDCIFGKR QSKKTPEGDA SPSTPEENET TTTSAFTIQE YFAKRMAALK NKPQVPVPGS DISETQVERK RGKKINKEAT GKDVESYLQP KAKRHTEGKP ERAEAQERVA KKKSAPAEEQ LRGPCWDQSS KASAQDAGDH VQPPEGRDFT LKPKKRRGKK KLQKPVEIAE DATLEETLVK KKKKKDSK
Molecular weight:
(348 aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing, 1 mM DTT, 10% glycerol
Endotoxin level:
< 1.0 EU per 1 µg of protein (determined by LAL method )
Purity:
>95% by SDS - PAGE
State:
Liquid purified protein
Purified
  • LinkedIn