AR09198PU-N IFNB / Interferon beta (22-182, His-tag)

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0.1 mg / €320.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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IFNB / Interferon beta

Product Description for IFNB / Interferon beta

IFNB / Interferon beta.
Presentation: Purified

Properties for IFNB / Interferon beta

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms Fibroblast interferon, IFB, IFN-beta, IFNB1
Presentation Purified
Molecular weight 22.0 kDa
Source E. coli
Species (Protein) Mouse
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P01575
Purity > 95 % by SDS - PAGE
Background Interferon beta 1, also known as IFN-beta, is produced mainly by fibroblasts and some epithelial cell types. IFN-beta is involved in the regulation of unspecific humoral immune responses and immune responses against viral infections. It also increases the expression of HLA class I antigens and blocks the expression of HLA class II antigens stimulated by IFN-gamma. Interferon beta 1 can be used for topic treatment of condylomata acuminata. Some studies suggest that Interferon beta 1 tends to prevent disease activity in patients with multiple sclerosis.
Concentration 0.25 mg/ml (determined by Bradford assay)
General Readings
  1. Fierlbeck G, d'Hoedt B, Stroebel W, Stutte H, Bogenschütz O, Rassner G. [Intralesional therapy of melanoma metastases with recombinant interferon-beta]. Hautarzt. 1992 Jan;43(1):16-21. PubMed PMID: 1612904.
  2. Panitch HS. Interferons in multiple sclerosis. A review of the evidence. Drugs. 1992 Dec;44(6):946-62. PubMed PMID: 1282865.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant Mouse Interferon beta 1 protein, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MINYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN
Molecular weight:
(182 aa), confirmed by MALDI-TOF
Format
Buffer System:
20mM HEPES (pH 6.0), 0.5M NaCl, 10% glycerol
Endotoxin level:
< 1.0 EU per 1 µg of protein (determined by LAL method )
Purity:
>95% by SDS - PAGE
State:
Liquid purified protein
Purified
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