CXCL12 / SDF1 (22-93, His-tag) - AR09203PU-N

Product Description for CXCL12 / SDF1

CXCL12 / SDF1.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	50 µg
Synonyms	C-X-C motif chemokine 12, IRH, Intercrine reduced in hepatomas, PBSF, Pre-B cell growth-stimulating factor, SDF1A, SDF1B, Stromal cell-derived factor 1, hIRH
Presentation	Purified
Molecular weight	10.8 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P48061
Purity	> 90 % by SDS - PAGE
Background	SDF-1 is a small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). SDF-1 is strongly chemotactic for lymphocytes and works by its receptor CXCR4. The SDF-1+CXCR4 complex plays a significant role in the creation of metastases of neoplasms and as a response to cytostatic treatment. Identification of this complex may be a useful prognostic factor in the therapy of many types of carcinoma.
Concentration	0.5 mg/ml (determined by Absorbance at 280nm)
General Readings	Arya M., et al. (2007). Tumour Biol. 28(3):123-31. Kucia M., et al. (2005). Stem Cells. 23(7):879-94.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human SDF-1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MKPVSLSYRC PCRFFESHVA RANVKHLKIL NTPNCALQIV ARLKNNNRQV CIDPKLKWIQ EYLEKALNKR FKM` Molecular weight: (93 aa), confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol Endotoxin level: < 1.0 EU per 1 µg of protein (determined by LAL method ) Purity: >90% by SDS - PAGE State: Liquid purified peptide Purified