AR09204PU-N Chromogranin A (19-457, His-tag)

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50 µg / €400.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Chromogranin A

Product Description for Chromogranin A

Chromogranin A.
Presentation: Purified

Properties for Chromogranin A

Product Category Proteins & Growth Factors
Quantity 50 µg
Synonyms CHGA, CgA, Chromogranin-A, Pituitary secretory protein I, SP-I
Presentation Purified
Molecular weight 51.2 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P10645
Purity > 80 % by SDS - PAGE
Background Chromogranin A is a member of the chromogranin/secretogranin (granins) family of neuroendocrine secretory proteins. Chromogranin A (CgA) represents the major soluble protein co-stored and co-released with catecholamines, within chromaffin cells secretory granules. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. It is considered a diagnostic and prognostic marker of several diseases, including a variety of tumours and cardiac heart failure.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings Ohyama C. et al. (1998) J Biol Chem. 273: 14582-14587. Moriwaki K. et al. (2009) Gastroenterology 137: 188-198.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human Chromogranin A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MLPVNSPMNK GDTEVMKCIV EVISDTLSKP SPMPVSQECF ETLRGDERIL SILRHQNLLK ELQDLALQGA KERAHQQKKH SGFEDELSEV LENQSSQAEL KEAVEEPSSK DVMEKREDSK EAEKSGEATD GARPQALPEP MQESKAEGNN QAPGEEEEEE EEATNTHPPA SLPSQKYPGP QAEGDSEGLS QGLVDREKGL SAEPGWQAKR EEEEEEEEEA EAGEEAVPEE EGPTVVLNPH PSLGYKEIRK GESRSEALAV DGAGKPGAEE AQDPEGKGEQ EHSQQKEEEE EMAVVPQGLF RGGKSGELEQ EEERLSKEWE DSKRWSKMDQ LAKELTAEKR LEGQEEEEDN RDSSMKLSFR ARAYGFRGPG PQLRRGWRPS SREDSLEAGL PLQVRGYPEE KKEEEGSANR RPEDQELESL SAIEAELEKV AHQLQALRRG
Molecular weight:
(460 aa)<br />(Molecular weight on SDS-PAGE will appear higher).
Format
Buffer System:
20mM Tris-HCl (pH 7.5) containing 2mM EDTA, 0.1mM PMSF, 10% Glycerol
Purity:
>80% by SDS - PAGE
State:
Liquid purified protein
Purified
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