discontinued

AP07350PU-N LRP6 (1546-1560) antibody

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Quick Overview

Rabbit anti Human LRP6

Product Description for LRP6

Rabbit anti Human LRP6.
Properties: (1546-1560)
Presentation: Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections.

Properties for LRP6

Product Category Primary Antibodies
Quantity 50 µg
Synonyms LRP-6, Low-density lipoprotein receptor-related protein 6
Presentation Purified
Reactivity Hu
Applications E, P
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O75581
Immunogen:
Synthetic peptide from human LRP6
GeneID:
4040
Property 1546-1560
Application ELISA: 1/1000.
Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Background LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.
Concentration 1 mg/ml
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein G column
Buffer System:
PBS with 0.09% (w/v) sodium azide
State:
Liquid purified Ig
Purified
Species Reactivity
Species reactivity (tested):
Human
Specificity
Specificity:
This antibody reacts to amino acids 1546 to 1560 of LRP6.
Gene ID 4040

Accessory Products

Proteins and/or Positive Controls

Positive controls for LRP6 (2 products)

Catalog No. Species Pres. Purity   Source  

LRP6 Lysate

Western Blot: LRP6 Lysate [NBL1-12672] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for LRP6
  Novus Biologicals Inc.

LRP6 overexpression lysate

LRP6 overexpression lysate
0.1 mg / €495.00
  OriGene Technologies, Inc.
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