Heme oxygenase 2 (HMOX2) (1-264) - AR09369PU-L

Product Description for Heme oxygenase 2 (HMOX2)

Heme oxygenase 2 (HMOX2).
Presentation: Purified

Immunogen	Swiss Prot Num: P30519
Purity	> 90 % by SDS – PAGE
Background	HMOX2 is microsomal enzyme that cleave heme ring at the alpha methane bridge to produce the antioxidant biliverdin, inorganic iron and carbon monoxide. Biliverdin is subsequently converted to bilirubin by bilibverdin reductase. This protein appears to be constitutively expressed in mammalian tissues. HMOX2 is involved in the production of carbon monoxide (CO) in brain, where CO is thought to act as a neurotransmitter.
Concentration	1.0 mg/ml (determined by Bradford assay)
General Readings	Baranano DE., et al. (2001) Proc Natl Acad Sci U S A. 98(20):10996-1002. Dore S., et al. (2002) Free Radic Biol Med. 32(12):1276-82.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant HMOX2 protein was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MSAEVETSEG VDESEKKNSG ALEKENQMRM ADLSELLKEG TKEAHDRAEN TQFVKDFLKG NIKKELFKLA TTALYFTYSA LEEEMERNKD HPAFAPLYFP MELHRKEALT KDMEYFFGEN WEEQVQCPKA AQKYVERIHY IGQNEPELLV AHAYTRYMGD LSGGQVLKKV AQRALKLPST GEGTQFYLFE NVDNAQQFKQ LYRARMNALD LNMKTKERIV EEANKAFEYN MQIFNELDQA GSTLARETLE DGFPVHDGKG DMRK` Molecular weight: (264 aa)
Format	Buffer System: 20 mM Tris buffer (pH 8.0) containing 10% glycerol, 1 mM DTT Purity: >90% by SDS – PAGE State: Liquid purified protein Purified