AM09127SU-N Desmoplakin (2115-2132) antibody

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5 ml / €300.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Mouse anti Bovine, Chicken, Fish, Human, Mouse, Xenopus, Zebrafish Desmoplakin DP447

AM09127SU-N

Product Description for Desmoplakin

Mouse anti Bovine, Chicken, Fish, Human, Mouse, Xenopus, Zebrafish Desmoplakin DP447.
Properties: (2115-2132)
Presentation: Supernatant
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.

Properties for Desmoplakin

Product Category Primary Antibodies
Quantity 5 ml
Synonyms 250/210 kDa paraneoplastic pemphigus antigen, DP, DSP
Presentation Supernatant
Reactivity Bov, Chk, Fi, Hu, Ms, Xen, Ze
Applications C, ICC/IF, P, WB
Clonality Monoclonal
Clone DP447
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P15924
Immunogen:
Synthetic peptide of human desmoplakin 2 (aa 2115-2132)
GeneID:
1832
Property 2115-2132
Application Immunoblotting
Immunofluorescence
Immunohistochemistry on frozen and Paraffin sections: Ready-to-use, with Paraffin use the microwave retrieval method.
General Readings
  1. Franke WW, Borrmann CM, Grund C, Pieperhoff S. The area composita of adhering junctions connecting heart muscle cells of vertebrates. I. Molecular definition in intercalated disks of cardiomyocytes by immunoelectron microscopy of desmosomal proteins. Eur J Cell Biol. 2006 Feb;85(2):69-82. Epub 2006 Jan 9. PubMed PMID: 16406610.
  2. Borrmann CM, Grund C, Kuhn C, Hofmann I, Pieperhoff S, Franke WW. The area composita of adhering junctions connecting heart muscle cells of vertebrates. II. Colocalizations of desmosomal and fascia adhaerens molecules in the intercalated disk. Eur J Cell Biol. 2006 Jun;85(6):469-85. Epub 2006 Apr 4. PubMed PMID: 16600422.
  3. Franke WW, Schumacher H, Borrmann CM, Grund C, Winter-Simanowski S, Schlechter T, et al. The area composita of adhering junctions connecting heart muscle cells of vertebrates - III: assembly and disintegration of intercalated disks in rat cardiomyocytes growing in culture. Eur J Cell Biol. 2007 Mar;86(3):127-42. Epub 2007 Feb 1. PubMed PMID: 17275137.
  4. Pieperhoff S, Franke WW. The area composita of adhering junctions connecting heart muscle cells of vertebrates - IV: coalescence and amalgamation of desmosomal and adhaerens junction components - late processes in mammalian heart development. Eur J Cell Biol. 2007 Jul;86(7):377-91. Epub 2007 May 29. PubMed PMID: 17532539.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
State:
Liquid culture supernatant containing 0.09% sodium azide
Supernatant
Specificity
Specificity:
The antibody shows distinct punctate membrane staining of different epithelia. Area compositae of the myocardium of higher vertebrates are also positive. The epitope is located in a region highly conserved among species (human, zebrafish).
Reacts on several cultured cell lines: Human MCF-7, A-431, HaCaT, CaCo2; Bovine MDBK, BMGE; Rainbow trout RTG-2.
Polypeptides reacting: Desmoplakin 1 and 2
Species:
Human, Bovine, Mouse, Chicken, Zebra fish, Rainbow trout, Xenopus l.
Gene ID 1832

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