Switch to Europe/Worldwide website Switch to German website Switch to French website Switch to OriGene Technologies, Inc. (North America)
Home » Plakophilin-4

AM09132SU-N Plakophilin-4 (85-104) antibody

See related secondary antibodies

Search for all "Plakophilin-4"

5 ml / €300.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

View Datasheet

Published recently!

Quick Overview

Mouse anti Bovine, Human, Mouse Plakophilin-4 7.7.9 (p0071-1)

AM09132SU-N

Product Description for Plakophilin-4

Mouse anti Bovine, Human, Mouse Plakophilin-4 7.7.9 (p0071-1).
Properties: (85-104)
Presentation: Supernatant
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.

Properties for Plakophilin-4

Product Category Primary Antibodies
Quantity 5 ml
Synonyms PKP4, p0071
Presentation Supernatant
Reactivity Bov, Hu, Ms
Applications C, ICC/IF, P, WB
Clonality Monoclonal
Clone 7.7.9 (p0071-1)
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q99569
Immunogen:
Synthetic peptide of human p0071 (aa position 85-104: EKSFPWRSTDVNTGVSKPR)
GeneID:
8502
Property 85-104
Application Immunoblotting: 1/10-1/50.
Immunofluorescence: Undiluted.
Immunohistochemistry on Frozen Sections: Undiluted.
Immunohistochemistry on Paraffin Sections:
Incubation Time: 1-1.5 h at RT. 
Positive Control: MCF-7 cells.
Background Plakophilin 4 (PKP4) is an Armadillo-like protein, characterized by a series of armadillo repeats. It is a component of desmosomal plaques and may play a role in junctional plaque organization.
Product Citations
Purchased from Acris:
  1. Todorović V, Koetsier JL, Godsel LM, Green KJ. Plakophilin 3 mediates Rap1-dependent desmosome assembly and adherens junction maturation. Mol Biol Cell. 2014 Sep 10. pii: mbc.E14-05-0968. PubMed PMID: 25208567.
General Readings
  1. Hofmann I, Schlechter T, Kuhn C, Hergt M, Franke WW. Protein p0071 - an armadillo plaque protein that characterizes a specific subtype of adherens junctions. J Cell Sci. 2009 Jan 1;122(Pt 1):21-4. doi: 10.1242/jcs.043927. PubMed PMID: 19092057.
  2. Hofmann I, Kuhn C, Franke WW. Protein p0071, a major plaque protein of non-desmosomal adhering junctions, is a selective cell-type marker. Cell Tissue Res. 2008 Dec;334(3):381-99. doi: 10.1007/s00441-008-0725-2. Epub 2008 Nov 13. PubMed PMID: 19005682.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Preservatives:
0.09% Sodium Azide
State:
Liquid Hybridoma Culture Supernatant
Supernatant
Species Reactivity
Species reactivity (tested):
Human, Bovine and Mouse
Specificity
Specificity:
This antibody recognizes Plakophilin-4. 
Detects a plaque protein (p0071) specific for a subtype of adherens junctions, with a molecular mass of 135 kD and is closely related to neurojungin / delta-catenin and ARVC (all belonging to the p120 armadillo subfamily). p0071 is specifically detected in the plaques of the composite junctions (area compositae) of cardiac intercalated disks, in puncta adhaerentia of single- and multi-layered epithelia and blood vessel endothelial cells.; it is, however, absent from desmosomes. This protein was also described as plakophilin 4.
Tested Reactivities on Cultured Cell Lines:MCF-7, A431, CaCo-2, HT-29, PLC, 16HBE14o, HaCaT, SV80,
 U333 CG, 3T3, RVF-SMC, MH1C1.
Gene ID 8502

Accessory Products

Proteins and/or Positive Controls

Proteins for Plakophilin-4 (2 products)

Catalog No. Species Pres. Purity   Source  

Plakophilin-4
Plakophilin-4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Plakophilin-4
Plakophilin-4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Recommended Secondary Antibodies for Plakophilin-4 (11 products)

Catalog No. Host Clone/Iso. Pres.   React. Applications  

Mouse IgG (H+L chain) antibody
Mouse IgG (H+L chain) antibody Rabbit AP C, E, WB
    OriGene Technologies GmbH

Mouse IgG (H+L chain) antibody
Mouse IgG (H+L chain) antibody Rabbit Biotin C, E, WB
    OriGene Technologies GmbH

Mouse IgG (H+L chain) antibody
Mouse IgG (H+L chain) antibody Rabbit FITC E, ICC/IF
    OriGene Technologies GmbH

Mouse IgG (H+L chain) antibody
Mouse IgG (H+L chain) antibody Rabbit HRP C, E, WB
    OriGene Technologies GmbH

Mouse IgG (H+L chain) antibody
Mouse IgG (H+L chain) antibody Rabbit Texas Red ICC/IF
    OriGene Technologies GmbH

Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody Rabbit PE F
    OriGene Technologies GmbH

Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody Goat PE
    OriGene Technologies GmbH

Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody Donkey PE
    OriGene Technologies GmbH

Mouse IgG (H+L chain), adsorbed antibody
Mouse IgG (H+L chain), adsorbed antibody Goat Cy2
    OriGene Technologies GmbH

Mouse IgG (H+L chain), adsorbed antibody
Mouse IgG (H+L chain), adsorbed antibody Goat Cy3
    OriGene Technologies GmbH

Mouse IgG (H+L chain), adsorbed antibody
Mouse IgG (H+L chain), adsorbed antibody Goat Cy5
    OriGene Technologies GmbH
Click here to see all secondary antibodies for Plakophilin-4
Compare Products

You have no items to compare.

My Cart

You have no items in your shopping cart.

Service
  • OriGene Technologies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
© Copyright 1998 - 2018 OriGene Technologies GmbH
  • LinkedIn