Product Description for Plakophilin-2
Mouse anti Bovine, Human, Mouse, Rat Plakophilin-2 Pkp2-518.
Properties: (527-872)
Presentation: Supernatant
Product is tested for Immunoelectron Microscopy, Immunoprecipitation, Frozen Sections, Paraffin Sections, Western blot / Immunoblot.
Properties: (527-872)
Presentation: Supernatant
Product is tested for Immunoelectron Microscopy, Immunoprecipitation, Frozen Sections, Paraffin Sections, Western blot / Immunoblot.
Properties for Plakophilin-2
| Product Category | Primary Antibodies |
|---|---|
| Quantity | 5 ml |
| Synonyms | PKP2 |
| Presentation | Supernatant |
| Reactivity | Bov, Hu, Ms, Ovine, Rt |
| Applications | C, EM, IP, P, WB |
| Clonality | Monoclonal |
| Clone | Pkp2-518 |
| Host | Mouse |
| Isotype | IgG1 |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Monoclonal Antibodies (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Property | 527-872 |
| Add. information | Mr ~100 kD (SDS-PAGE) MW calculated from aa sequence: 92,750 (pI 9.33) and 97,410 (pI 9.38). |
| Application | Western Blot. Immunoprecipitation. Immunoelectron Microscopy. Immunohistochemistry on Frozen and Paraffin-Embedded Sections (after microwave treatment). For better accessibility of the desmosome-associated antigen frozen sections might be pre-incubated for 5 min in PBS plus 0.2% Triton X-100 prior to antibody application. Longer incubation could result in a loss of Pkp2-nuclear staining. To prevent wash-out of soluble forms of the antigen, fixation with 2% formaldehyde is recommended. Working Dilution: Ready-to-use for Immunohistochemistry Tested Reactivities on Cultured Cell Lines: Human: HaCaT, PLC, MCF-7 Human, Bovine, Ovine cardiac myocytes. |
| Background | Plakophilin 2 is a member of the arm-repeat family of proteins which can occur in at least 2 splice forms (2a and 2b). Plakophilin 2 assembles with other proteins to form the desmosomal plaque in simple and glandular epithelia, the basal layer of certain stratified epithelia, all layers of some stratified epithelia, and desmosomepossessing nonepithelial cells such as myocardium, Purkinje fibers, and dendritic reticulum of lymph node follicles. In all these cells, including a variety of cell types devoid of desmosomes, plakophilin 2 is highly enriched in the karyoplasm. |
| General Readings |
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| Storage | Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch. |
| Format |
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| Species Reactivity |
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| Specificity |
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Accessory Products
Proteins and/or Positive Controls
Positive controls for Plakophilin-2 (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| LY423822 |
PKP2 overexpression lysate |
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 |
0.1 mg /
€295.00
|
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| OriGene Technologies, Inc. | |||||||
Recommended Secondary Antibodies for Plakophilin-2 (11 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1253AP |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | AP | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253B |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Biotin | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253F |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | FITC | E, ICC/IF | ||||
| OriGene Technologies GmbH | |||||||
| R1253HRP |
Mouse IgG (H+L chain) antibody |
||||||
|
Rabbit | HRP | C, E, WB | ||||
| OriGene Technologies GmbH | |||||||
| R1253TR |
Mouse IgG (H+L chain) antibody |
||||||
|
|
Rabbit | Texas Red | ICC/IF | ||||
| OriGene Technologies GmbH | |||||||
| R1403R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
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|
|
Rabbit | PE | F | ||||
| OriGene Technologies GmbH | |||||||
| R1405R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
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|
|
Goat | PE | |||||
| OriGene Technologies GmbH | |||||||
| R1455R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
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|
|
Donkey | PE | |||||
| OriGene Technologies GmbH | |||||||
| R1457C2 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy2 | |||||
| OriGene Technologies GmbH | |||||||
| R1457C3 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy3 | |||||
| OriGene Technologies GmbH | |||||||
| R1457C5 |
Mouse IgG (H+L chain), adsorbed antibody |
||||||
|
|
Goat | Cy5 | |||||
| OriGene Technologies GmbH | |||||||
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