Product Description for SAT1
SAT1.
Presentation: Purified
Presentation: Purified
Properties for SAT1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | Diamine acetyltransferase 1, Polyamine N-acetyltransferase 1, Putrescine acetyltransferase, SAT, SSAT, SSAT-1, Spermidine/spermine N(1)-acetyltransferase 1 |
| Presentation | Purified |
| Molecular weight | 22.1 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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|---|---|
| Purity | > 95 % by SDS - PAGE |
| Background | Diamine N-acetyltransferase 1 (or Spermidine/spermine-N1-acetyltransferase, SSAT1), as known as SAT-1, is a polyamine catabolic enzyme which catalyzes the acetylation of polyamines. This protein plays an important role in polyamine homoeostasis, since acetylated products are either excreted from the cell or oxidized by acetylpolyamine oxidase. A variety of other effects of increased SAT-1 activity include death of pancreatic cells, blockage of regenerative tissue growth, behavioral changes, keratosis follicularis spinulosa decalvans (KFSD), and hair loss. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Pegg AE., et al. (2008). Am J Physiol Endocrinol Metab. 294: E995-E1010. Jänne J., et al. (2006). J Cell Mol Med. 10(4):933-45. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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