AR09563PU-N CKBB (1-381, His-tag)

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0.1 mg / €320.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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CKBB

AR09563PU-N

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  • AR09563PU-N

Product Description for CKBB

CKBB.
Presentation: Purified

Properties for CKBB

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms B-CK, CKB, Creatine kinase B chain, Creatine kinase B-type, Creatine kinase BB
Presentation Purified
Molecular weight 44.8 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P12277
Purity > 95 % by SDS - PAGE
Background CKB (Creatine kinase B-type) is a cytoplasmic enzyme involved in energy homeostasis. The protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. Creatine kinases provide the energy of phosphate hydrolysis necessary to drive the normal function of many cellular systems including muscle, tumor and cancer cells.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Chang EJ., et al. (2008) Nat Med. 14(9):966-72.
Debrincat MA., et al. (2007) J Biol Chem. 282(7):4728-37.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human CKB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography technique.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MPFSNSHNAL KLRFPAEDEF PDLSAHNNHM AKVLTPELYA ELRAKSTPSG FTLDDVIQTG VDNPGHPYIM TVGCVAGDEE SYEVFKDLFD PIIEDRHGGY KPSDEHKTDL NPDNLQGGDD LDPNYVLSSR VRTGRSIRGF CLPPHCSRGE RRAIEKLAVE ALSSLDGDLA GRYYALKSMT EAEQQQLIDD HFLFDKPVSP LLLASGMARD WPDARGIWHN DNKTFLVWVN EEDHLRVISM QKGGNMKEVF TRFCTGLTQI ETLFKSKDYE FMWNPHLGYI LTCPSNLGTG LRAGVHIKLP NLGKHEKFSE VLKRLRLQKR GTGGVDTAAV GGVFDVSNAD RLGFSEVELV QMVVDGVKLL IEMEQRLEQG QAIDDLMPAQ K
Molecular weight:
(401aa), confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 10% glycerol
Purity:
>95% by SDS - PAGE
State:
Liquid purified protein
Purified
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