AR09568PU-N HTATIP2 (1-242, His-tag)

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0.1 mg / €320.00
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HTATIP2

AR09568PU-N

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  • AR09568PU-N

Product Description for HTATIP2

HTATIP2.
Presentation: Purified

Properties for HTATIP2

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms 30 kDa HIV-1 TAT-interacting protein, CC3, HIV-1 TAT-interactive protein 2, Oxidoreductase HTATIP2, TIP30
Presentation Purified
Molecular weight 29.3 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9BUP3
Purity > 95 % by SDS – PAGE
Background HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy.
Concentration 1.0 mg/ml (determined by Bradford assay)
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human HTATIP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MAETEALSKL REDFRMQNKS VFILGASGET GRVLLKEILE QGLFSKVTLI GRRKLTFDEE AYKNVNQEVV DFEKLDDYAS AFQGHDVGFC CLGTTRGKAG AEGFVRVDRD YVLKSAELAK AGGCKHFNLL SSKGADKSSN FLYLQVKGEV EAKVEELKFD RYSVFRPGVL LCDRQESRPG EWLVRKFFGS LPDSWARGHS VPVVTVVRAM LNNVVRPRDK QMELLENKAI HDLGKAHGSL KP
Molecular weight:
(262aa), confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1 mM DTT
Purity:
>95% by SDS – PAGE
State:
Liquid purified protein
Purified
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