Product Description for WDR5 / BIG3
WDR5 / BIG3.
Presentation: Purified
Presentation: Purified
Properties for WDR5 / BIG3
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | BIG-3, BMP2-induced 3-kb gene protein, WD repeat-containing protein 5 |
| Presentation | Purified |
| Molecular weight | 38.8 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 95 % by SDS – PAGE |
| Background | WDR5, also designated BMP-2-induced gene 3 kb or BIG-3, belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. This protein is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. WDR5 may play a role in its function of accelerating osteoblast differentiation. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Yokoyama., et al. (2004) Mol Cell Biol. 24(13):5639-49. Gori F., et al. (2001) J Biol Chem. 276(49):46515-22. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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