AR09570PU-N NUDT5 (1-219, His-tag)

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0.1 mg / €320.00
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NUDT5

AR09570PU-N

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  • AR09570PU-N

Product Description for NUDT5

NUDT5.
Presentation: Purified

Properties for NUDT5

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms ADP-sugar pyrophosphatase, Nucleoside diphosphate-linked moiety X motif 5, Nudix motif 5, YSA1H
Presentation Purified
Molecular weight 26.5 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9UKK9
Purity > 85 % by SDS – PAGE
Background NUDT5 is a member of the nudix hydrolase family which eliminate toxic nucleotide derivatives from the cell. NUDT5 hydrolyzes ADP-ribose and ADP-mannose in the presence of magnesium, and also hydrolyzes other nucleotide sugars with low activity such as ADP-glucose and diadenosine diphosphate. As a nudix hydrolase, NUDT5 contains a central nudix motif and functions to eliminate toxic nucleotide metabolites from the cell while maintaining the levels of signaling nucleotides. NUDT5 is widely expressed but is most abundant in liver as a homodimer.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Yu HN., et al. (2007) Biochem Biophys Res Commun. 354(3):764-8.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human NUDT5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MESQEPTESS QNGKQYIISE ELISEGKWVK LEKTTYMDPT GKTRTWESVK RTTRKEQTAD GVAVIPVLQR TLHYECIVLV KQFRPPMGGY CIEFPAGLID DGETPEAAAL RELEEETGYK GDIAECSPAV CMDPGLSNCT IHIVTVTING DDAENARPKP KPGDGEFVEV ISLPKNDLLQ RLDALVAEEH LTVDARVYSY ALALKHANAK PFEVPFLKF
Molecular weight:
(239aa), confirmed by MALDI-TOF (real molecular weight on SDS-PAGE will be shift up).
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1 mM DTT, 0.1 M NaCl
Purity:
>85% by SDS – PAGE
State:
Liquid purified protein
Purified
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