PEA15 (1-130) - AR09282PU-N | acris-antibodies.com

Product Description for PEA15

PEA15.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	Astrocytic phosphoprotein PEA-15, PED, Phosphoprotein enriched in diabetes
Presentation	Purified
Molecular weight	kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q15121
Purity	> 90 % by SDS - PAGE
Background	Phospho-enriched protein in astrocytes 15 kDa (PEA-15) is a death effector domain (DED)-containing protein predominantly expressed in the central nervous system, particularly in astrocytes. This protein has been implicated in the regulation of multiple cellular processes including apoptosis, proliferation, glucose transport, adhesion and migration. Increased PEA-15 levels may affect tumorigenesis and cancer progression, thus it is overexpressed in breast cancers and gliomas as well as in type 2 diabetes.
Concentration	1.0 mg/ml (determined by Bradford assay)
General Readings	Beguinot F., et al. (2009) Am J Physiol Endocrinol Metab. 297(3):E592-601. Ueno NT., et al. (2008) Cancer Res. 68(22):9302-10.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human PEA-15 was expressed in E.coli and purified by using conventional chromatography. AA Sequence: `MAEYGTLLQD LTNNITLEDL EQLKSACKED IPSEKSEEIT TGSAWFSFLE SHNKLDKDNL SYIEHIFEIS RRPDLLTMVV DYRTRVLKIS EEDELDTKLT RIPSAKKYKD IIRQPSEEEI IKLAPPPKKA` Molecular weight: (130 aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 7.5) containing 1 mM DTT, 10% Glycerol Purity: >90% by SDS - PAGE State: Liquid purified protein Purified