AR09422PU-N NQO2 (1-231, His-tag)

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0.1 mg / €290.00
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NQO2

AR09422PU-N

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  • AR09422PU-N

Product Description for NQO2

NQO2.
Presentation: Purified

Properties for NQO2

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms NMOR2, NRH dehydrogenase [quinone] 2, NRH:quinone oxidoreductase 2, Ribosyldihydronicotinamide dehydrogenase [quinone]
Presentation Purified
Molecular weight 28.1 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P16083
Purity > 95 % pure by SDS–PAGE
Background NQO2 is a member of the NAD(P)H dehydrogenase (quinone) . The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. It is flavoproteins that catalyze the metabolic detoxification of quinones and their derivatives to hydroquinones. This detoxification process protects cells against quinone-induced oxidative stress, cytotoxicity and mutagenicity.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings
  1. Wu K., et al. (1997) Arch Biochem Biophys. 347(2):221-8.
  2. Jaiswal AK., et al. (1994) J Biol Chem. 269(20):14502-8.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant Human NQO2 protein, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MAGKKVLIVY AHQEPKSFNG SLKNVAVDEL SRQGCTVTVS DLYAMNFEPR ATDKDITGTL SNPEVFNYGV ETHEAYKQRS LASDITDEQK KVREADLVIF QFPLYWFSVP AILKGWMDRV LCQGFAFDIP GFYDSGLLQG KLALLSVTTG GTAEMYTKTG VNGDSRYFLW PLQHGTLHFC GFKVLAPQIS FAPEIASEEE RKGMVAAWSQ RLQTIWKEEP IPCTAHWHFG Q
Molecular weight:
(251 aa), confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1 mM DTT
Purity:
>95% pure by SDS–PAGE
State:
Liquid purified protein
Purified
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