SKP1 / OCP2 (1-160) - AR09313PU-L | acris-antibodies.com

Product Description for SKP1 / OCP2

SKP1 / OCP2.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.5 mg
Synonyms	Cyclin A/CDK2-associated protein p19, EMC19, OCP-2, OCP-II, Organ of Corti protein 2, RNA polymerase II elongation factor-like protein, S-phase kinase-associated protein 1, SKP1A, TCEB1L, Transcription elongation factor B, p19A, p19skp1
Presentation	Purified
Molecular weight	kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P63208
Purity	> 90 % by SDS - PAGE
Background	S-phase kinase-associated protein 1, also known as SKP1, is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to proteins containing an F-box motif, such as cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin dependent proteolysis. It is also involved in the control of beta-catenin levels and the activity of beta-catenin dependent TCF transcription factors.
Concentration	1.0 mg/ml (determined by Bradford assay)
General Readings	Min KW., et al. (2003) J Biol Chem. 278(18):15905-10.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human SKP1 protein was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MPSIKLQSSD GEIFEVDVEI AKQSVTIKTM LEDLGMDDEG DDDPVPLPNV NAAILKKVIQ WCTHHKDDPP PPEDDENKEK RTDDIPVWDQ EFLKVDQGTL FELILAANYL DIKGLLDVTC KTVANMIKGK TPEEIRKTFN IKNDFTEEEE AQVGSTQFCL` Molecular weight: (160 aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 50 mM NaCl, 10% glycerol Purity: >90% by SDS - PAGE State: Liquid purified protein Purified