AR09032PU-L Somatotropin / Growth Hormone / GH1 (20 kDa Variant)

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0.5 mg / €600.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Somatotropin / Growth Hormone / GH1

Product Description for Somatotropin / Growth Hormone / GH1

Somatotropin / Growth Hormone / GH1.
Presentation: Purified

Properties for Somatotropin / Growth Hormone / GH1

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Synonyms Growth hormone 1, HGH, Pituitary growth hormone
Presentation Purified
Molecular weight 20 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P01241
Purity > 95 % pure by SDS PAGE
Background The 20KDa variant form of human growth hormone (20KDa hGH) presents in extracts from pituitary glands and it differs from the major form of hGH (22K, 191 amino acid) by the deletion of amino acid residues 32-46. The physiological role of 20K hGH remains to be determined partly but it regards the main function as stimulation of somatic and bone growth, as well as an increase in the size and mass of organs and tissues.
Concentration 1.0 mg/ml
General Readings Tsushima, et al (2000) Endocr J. 47; S17-21.
Horan, M.,et al(2003) Hum. Mutat.21(4), 408-423.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant 20 KDa human growth hormone was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
AA Sequence:
MFPTIPLSRL FDNAMLRAHR LHQLAFDTYQ EFNPQTSLCF SESIPTPSNR EETQQKSNLE LLRISLLLIQ SWLEPVQFLR SVFANSLVYG ASDSNVYDLL KDLEEGIQTL MGRLEDGSPR TGQIFKQTYS KFDTNSHNDD ALLKNYGLLY CFRKDMDKVE TFLRIVQCRS VEGSCGF
Biological activity:
Measured in a cell proliferation assay using Nb2-11 Rat lymphoma cells. The ED50 for this effect is less or equal to 1 ng/ml.
Molecular weight:
20 kDa (177 amino acids) confirmed by MALDI-TOF.
Format
Buffer System:
88 mM Mannitol, 5 mM phosphate, pH 7.4
Endotoxin level:
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity:
>95% pure by SDS PAGE
State:
Liquid purified protein
Purified
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