PPP1R1A (1-171, His-tag) - AR09053PU-N

Product Description for PPP1R1A

PPP1R1A.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	IPP-1, IPP1, Protein phosphatase 1 regulatory subunit 1A, Protein phosphatase inhibitor 1
Presentation	Purified
Molecular weight	kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q13522
Purity	≥ 90
Background	Protein phosphatase 1 regulatory subunit 1A (PPP1R1A, IPP-1) plays an important role in the regulation of glycogen metabolism through inhibition of type-1 protein serine/threonine phosphatase (PP1) activity, and it has been implicated in the regulation of cell growth. IPP-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. In the presence of calcium, PPI-1 is inactivated by calcineurin (or PP2B).
Concentration	1.0 mg/ml
General Readings	Weiser DC., et al. (2004), J. Biol. Chem. Nov 19;279(47):48904-14. Rodriguez P., et al. (2006), J. Biol. Chem. Dec 15;281(50):38599-608.
Storage	Store (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human IPP-1, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MEQDNSPRKI QFTVPLLEPH LDPEAAEQIR RRRPTPATLV LTSDQSSPEI DEDRIPNPHL KSTLAMSPRQ RKKMTRITPT MKELQMMVEH HLGQQQQGEE PEGAAESTGT QESRPPGIPD TEVESRLGTS GTAKKTAECI PKTHERGSKE PSTKEPSTHI PPLDSKGANS VLEHHHHHH` Molecular weight: (179 aa)
Format	Buffer System: 50 mM Tris pH 8.0, 0.1 mM PMSF, 1 mM EDTA, 1 mM DTT, 10% glycerol Purity: ≥90 State: Liquid purified protein Purified