BM3013 VZV / HHV-3 Ellen strain, Glycoprotein IV (GI) antibody

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0.5 mg / €520.00
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Mouse anti VZV / HHV-3 SG4

BM3013

Product Description for VZV / HHV-3

Mouse anti VZV / HHV-3 SG4.
Properties: Ellen strain, Glycoprotein IV (GI)
Presentation: Azide Free
Product is tested for Immunocytochemistry/Immunofluorescence, Immunoprecipitation.

Properties for VZV / HHV-3

Product Category Primary Antibodies
Quantity 0.5 mg
Synonyms HHV3, Varizella zoster
Presentation Azide Free
Applications ICC/IF, IP
Clonality Monoclonal
Clone SG4
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
VZV Ellen Strain from VZV-infected Monkey kidney cells (BSC-1).
Property Ellen strain, Glycoprotein IV, GI
Application Intended for detection of VZV glycoprotein IV (VZVgI) in cell culture by Indirect Immunofluorescent antibody technique and for Immunoprecipitation test.
Background Varicella Zoster Virus (VZV), a member of the human herpes virus family, causes two distinct clinical manifestations: childhood chickenpox(Varicella) and shingles (zoster). Varicella is the outcome of the primary infection with VZV, whereas, zoster is the result of VZV reactivation from latently infected sensory ganglia which occurs predominantly in aging and immunosuppressed individuals.
VZV is closely related to the herpes simplex viruses (HSV), sharing much genome homology. The known envelope glycoproteins (gB, gC, gE, gH, gI, gK, gL) correspond with those in HSV, however there is no equivalent of HSV gD.
VZV virons are spherical and 150-200 nm in diameter. Its lipid envelope encloses the nucleocapsid of 162 capsomeres arranged in a hexagonal form. Its DNA is a single linear, double strand molecule, 125,000 nt long.
Concentration 1.02 mg/ml (OD280nm, E0.1%=1.4)
General Readings 1. Weller, T.H., (1979), Varicella and Herpes Zoster. In:Diagnostic Procedures for Viral, Rickettsial and Chlamydial Infections, (Lennette, E.H. and Schmidt, N.J., eds.),
American Public Health Associations, Inc. Washington D.C., pp 375-398.
2. Drew, W.L., et al., (1980), Rapid diagnosis of varicella-zoster virus infection by direct immuno-fluorescence, Am. J. Clin. Pathol., 73:699-701.
3. Davison et al, (1986), New common nomenclature for glycoprotein gene of varicella-zoster virus and their glycosylated products, J. Virol., 57:1195-1197.
4. Sato, H., et al., (2003), “Varicella-Zoster Virus ORF47 Protein Kinase, which is required for Replication in Human T cells, and ORF66 Protein Kinase which is expressed during Latency, are dispensable for establishment of Latency”, Journal of Virology, 77(20): 11180-11185
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein G Chromatography
Buffer System:
20mM Na2HPO4, pH 9.0 without preservatives
State:
Liquid purified Ig fraction
Azide Free
Specificity
Specificity:
This antibody reacts with VZV glycoprotein IV (VZVgI) and to a lesser extent VZV glycoprotein I (VZVgE) by Immunoprecipitation test.
This clone reacts with both precursor and mature glycoprotein IV (VZVgI).

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