AR09009PU-L CIB1 (1-191, His-tag)

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0.5 mg / €820.00
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Quick Overview

CIB1

Product Description for CIB1

CIB1.
Presentation: Purified

Properties for CIB1

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Synonyms CIBP, Calcium and integrin-binding protein 1, Calmyrin, DNA-PKcs-interacting protein, KIP, Kinase-interacting protein, PRKDCIP, SIP2-28, SNK-interacting protein 2-28
Presentation Purified
Molecular weight 23 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q99828
Purity > 95 % pure by SDS PAGE
Add. information NCBI Accession : NP_006375
Background CIB1 (Calcium and integrin binding 1) is regulatory protein with 50% homology to calmodulin and calcineurin B, that encodes a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. Also CIB1 is widely expressed and binds to a number of effectors, such as integrin αIIb, PAK1, and polo-like kinases, in different tissues.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Yuan W , et al , (2006). Mol Cell Biochem. 26(22) : 8507.
Yuan , et al , (2006). J Cell Biol. 16;172(2) :169-75.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant Human CIB1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGGSGSRLSK ELLAEYQDLT FLTKQEILLA HRRFCELLPQ EQRTVESSLR AQVPFEQILS LPELKANPFK ERICRVFSTS PAKDSLSFED FLDLLSVFSD TATPDIKSHY AFRIFDFDDD GTLNREDLSR LVNCLTGEGE DTRLSASEMK QLIDNILEES DIDRDGTINL SEFQHVISRS PDFASSFKIV L
Molecular weight:
23 kDa (211 aa), confirmed by MALDI-TOF.
Format
Buffer System:
20 mM Tris pH 8.0, 5 mM DTT
Purity:
>95% pure by SDS PAGE
State:
Liquid purified protein
Purified
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